^(32)磷简易敷贴药膜治疗小儿皮肤血管瘤2450例疗效分析

Therapeutic Assessment of 2450 Cases of Little Children Hemangioma with ^(32)P Simple-drug Membranes

目的 评价3 2 磷简易敷贴药膜治疗小儿皮肤血管瘤的效果 .方法 2 4 5 0例不同年龄的血管瘤小儿接受3 2 磷简易敷贴药膜治疗 ,治疗次数为 1～ 9次 ,平均 3.5次 ;每次间隔 2个月 ,按不同年龄给不同的照射量 ,以治疗时间换算 ,每次治疗剂量为 0 .92 5MBq/cm2 × ( 12～ 4 2 )h .结果 血管瘤和血管痣治愈率 71.7% ,部分治愈 2 2 .5 % ,总有效率 94 .2 % ,无效者 5 .8% .其中血管瘤效果明显优于血管痣 (p<0 .0 1) ,并且年龄越小效果越明显 (p<0 .0 1) .结论 3 2 磷简易敷贴药膜治疗小儿皮肤血管瘤是一种治疗简便、疗效确切的方法 。

Objective To assess the therapeutic effects of treating little children hemangioma with 32 P simple-drug membranes. Methods 2450 cases with different age children were treated with 32 P simple-drug membranes, the treatment times range from 1 to 9, averaging 3.5 times. The interval between two treatment were three months. Children with different ages were received various radiation dosage, with each time 0.925MBq/cm 2×(12～42)h according to the exchange of treatment time(hours). Results Full cure rate was 71.7%, partly cure was 22.5% ,total effective rate was 94.2% and no effects 5.8%. Of which, patients with hemangioma got better effects than those with naevus flammeus (p<0.01), and the younger in age,the better in therapeutic effect(p<0.01). Conclusions The treatment of little children dermal hemangioma with 32 P simple-drug membranes was simple, and efficiency was high. We thought that the better results would be got as early as possible.