摘要
目的 :探讨对184例女性生殖道解脲脲原体感染者进行药物敏感性试验的结果分析。方法 :将2013年1月~2014年1月期间唐山市眼科医院妇科门诊收治的184例女性生殖道解脲脲原体阳性患者的临床资料进行回顾性研究。取这些患者的阴道分泌物,使用病原体鉴定药敏试剂盒进行药敏试验,并对其试验结果进行分析。结果 :这184例患者感染的病原体对四环素的敏感率为92.4%,对强力霉素的敏感率为88.0%,对美满霉素的敏感率为93.5%,对交沙霉素的敏感率为90.2%,对司帕沙星的敏感率为95.7%,对红霉素的耐药率为96.2%,对罗红霉素的耐药率为75.0%,对壮观霉素的耐药率为79.3%,对阿奇霉素的耐药率为7 6.6%。结论 :四环素类抗生素可作为治疗女性生殖道解脲脲原体感染患者的首选药物,交沙霉素可作为治疗女性生殖道解脲脲原体感染患者的经验用药。
Objective: In order to provide basis for clinical rational drug use, we analyze 184 ureaplasma urealyticum positive specimens collected from gynecological patients in Tangshan eye hospital from January 2012 to January 2013. METHODS: drug sensitivity tests through Mycoplasma identification and drug susceptibility kits.RESULT: Drug sensitivity of Tetracycline, doxycycline, minocycline, josamycin and sparfloxacin respectively are 92.4%, 88.0%, 93.5%, 90.2% and 95.7%; drug resistency rates of Erythromycin, roxithromycin, spectinomycin and azithromycin respectively are 96.2%, 75.0%, 79.3% and 76.6%. CONCLUSIONS: Tetracycline antibiotic is preferred drug for Ureaplasma urealyticum infections in reproductive tract; Josamycin is experienced application of Ureaplasma urealyticum infection; Though Quinolones are safe and have broad antibacterial spectrum in recent years, its increasing drug resistance rate limit its clinical application.
