联用甲氨蝶呤、米非司酮及中药治疗宫外孕的效果研究

Effect of methotrexate, mifepristone and Chinese medicine in the treatment of ectopic pregnancy

目的 :探讨分析联用甲氨蝶呤、米非司酮及中药治疗宫外孕的临床效果。方法 :选取2012年9月~2014年9月间我院收治的宫外孕患者68例作为研究对象,采用随机数字表法将其分为观察组(34例)和实验组(34例),联合使用甲氨蝶呤和米非司酮为观察组患者进行治疗,联合使用甲氨蝶呤、米非司酮及中药为实验组患者进行治疗,观察对比两组患者的临床疗效,并将对比的结果及两组患者的临床资料进行回顾性的分析。结果 :实验组患者治疗的总有效率为94.1%,观察组患者治疗的总有效率为73.5%,实验组患者的临床疗效明显优于观察组患者,差异显著(P<0.05),具有统计学意义。实验组患者的不良反应发生率为2.9%,观察组患者的不良反应发生率为14.7%,实验组患者的不良反应发生率明显低于观察组患者,差异显著(P<0.05),具有统计学意义。结论 :联用甲氨蝶呤、米非司酮及中药治疗宫外孕的临床效果显著,值得在临床上推广应用。

Popurse: To methotrexate and mifepristone investigate the therapeutic effect of combined traditional Chinese med icine (TCM) in patients with ectopic pregnancy. Selection methods: Chose 68 cases of ectopic pregnancy patients from Septembe r 2012 to September 2014, all patients were divided into two groups, the experimental group were treated by methotrexate and mi fepristone in combination with Chinese medicine treatment, the observation group were treated by methotrexate and mifepristone treatment, to compare the effect of two groups of patients. Results: the patients with the treatment effective rate was 94.1%; The&nbsp;control group, the treatment effective rate was 73.5% in patients with obvious differences comparing the two groups, P < 0.05). E xperimental group patients only 1 case of dizziness cases occurred, rate of 2.9%; In 2 cases of control group patients nausea, 2 c ases of diarrhea cases, 1 case of transaminase eleations, rate of 14.7%, there exists significant difference comparing the two grou ps, P < 0.05). Conclusion: methotrexate and mifepristone in combination with Chinese medicine treatment effect is very significa nt in ectopic pregnancy.