硫酸镁联合硝苯地平治疗妊娠期高血压疾病的疗效观察

Clinical observation on treatment of gestational hypertension with Magnesium sulfate combined with nifedipine

目的 :观察联合应用硫酸镁和硝苯地平治疗妊娠期高血压的疗效。方法 :对我院收治的102例妊娠期高血压患者的临床资料进行回顾性分析,将其分为对照组和观察组,每组各51例患者。为对照组患者使用硫酸镁进行治疗,为观察组患者联合应用硫酸镁和硝苯地平控释片进行治疗,并对比观察两组患者在进行治疗后血压改善的情况及各项临床指标。结果:在进行治疗前,两组患者的舒张压与收缩压相比较,差异不显著(P>0.05),无统计学意义。在进行治疗后,与对照组患者相比较,观察组患者的舒张压和收缩压较低,差异显著(P<0.05),有统计学意义。两组患者发生产后出血的几率相比较差异显著(P<0.05),有统计学意义。观察组患者并发症的发生率明显低于对照组患者,差异显著(P<0.05),有统计学意义。结论 :联合应用硫酸镁和硝苯地平治疗妊娠期高血压的效果显著,发生并发症的几率较低,此法值得在临床上推广应用。

Objective: to observe the curative effect of magnesium sulfate combined nifedipine treatment of pregnancy-induced hypertension syndrome. Method: choose 102 cases of pregnancy-induced hypertension syndrome patients as the research object, the patients were divided into control group and observation group, each group of patients, 51 patients with different drug therapy, observe two groups after treatment in patients with blood pressure and clinical indicators. Results: diastolic and systolic blood pressure after treatment group compared to control group antihypertensive effect differences statistically significant (P < 0.05), the observation group and control group in clinical complications compared statistically significant difference (P < 0.05). Conclusion: magnesium sulfate in combination with nifedipine treatment of pregnancy-induced hypertension syndrome, obvious effect and less complications, worthy of clinical popularization and application.