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血清孕酮、白细胞介素-8和肿瘤坏死因子-α与先兆流产的关联性分析 被引量:2

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摘要 目的 :分析血清孕酮、IL-8和TNF-α与先兆流产的关联性。方法 :对我院收治的34例先兆流产患者和34例难免流产患者的临床资料进行回顾性分析,将先兆流产患者作为实验A组,将难免流产患者作为实验B组,将在我院进行人工流产的34例正常早孕女性作为对照组,并采用ELSA法对其进行血清孕酮、IL-8和TNF-α检测。结果 :实验B组患者血清孕酮的水平明显低于实验A组患者,实验A组患者血清孕酮的水平明显低于对照组患者,差异显著(P<0.05),有统计学意义。实验B组患者IL-8和TNF-α的水平明显高于实验A组患者,实验A组患者IL-8和TNF-α的水平明显高于对照组患者,差异显著(P<0.05),有统计学意义。在实验A组患者中,有21例患者治疗成功,占61.8%;有12例患者发展成难免流产或胚胎停止发育,占35.3%。在进行治疗前后,实验A组患者血清IL-8和TNF-α的水平相比较,差异显著(P<0.05),有统计学意义。在进行治疗后,实验A组患者血清IL-8和TNF-α的水平与对照组患者相比较,差异不显著(P>0.05),无统计学意义。结论 :血清孕酮、IL-8和TNF-α指标可作为诊断先兆流产,评价先兆流产患者预后的重要标准。
作者 许云霞
机构地区 包头市
出处 《当代医药论丛》 2015年第10期55-56,共2页
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