应用奥施康定治疗中重度癌性疼痛的临床效果分析

Analysis of the clinical effect of application like Kangding in the treatment of moderate and severe cancer pain

目的:探讨应用奥施康定治疗中重度癌性疼痛的临床效果。方法 :对我院收治的80例发生中重度癌性疼痛的晚期癌症患者的临床资料进行回顾性分析,根据治疗方案的不同将其分为对照组和实验组,为对照组患者使用盐酸美沙酮片(美沙酮)进行治疗,为实验组患者使用奥施康定(盐酸羟考酮控释片)进行治疗,并对比分析其临床疗效。结果 :实验组患者癌性疼痛的缓解率明显高于对照组患者,差异显著(P<0.05),有统计学意义。在进行治疗后,实验组患者Karnofsky的评分明显高于对照组患者,差异显著(P<0.05),有统计学意义。实验组患者不良反应的发生率明显低于对照组患者,差异显著(P<0.05),有统计学意义。结论 :为中重度癌性疼痛患者采用奥施康定进行治疗的效果理想,可显著减轻其疼痛的症状,改善其生活质量,此法值得在临床上推广应用。

Objective: To investigate the clinical efficacy of Ochs Kangding in moderate to severe cancer pain patients. Methods: a total of 80 cases of advanced cancer patients data were analyzed according to different treatment regimens, the patients were divided into the control group and the experimental group, the control group using Methadone Hydrochloride Tablets(methadone) treatment, experimental group using oxy Kangding(oxycodone hydrochloride controlled-release tablets) treatment, compared two groups of curative effect. Results: in experiment group, pain relief rate was 92.5%, significantly higher than that in control group(pain relief rate was 80%(P<0.05)); the two groups before treatment Karnofsky score difference was not significant(P>0.05); the experimental group after treatment, Karnofsky score of(80 + 12), significantly higher than that in control group(70 + 11)(P<0.05) the experimental group; the incidence rate of adverse reaction was 7.5%, significantly higher than that of the control group(the incidence rate of adverse reaction was 17.5%(P<0.05)). Conclusion: in patients with severe cancer pain by Ochs Kangding ideal treatment effect, can reduce the pain of patients, improve the quality of life of patients, is worthy to be popularized.