用奥美拉唑治疗新生儿上消化道出血的效果研究

Effect of omeprazole in treatment of upper digestive tract hemorrhage in neonate

目的:探讨用奥美拉唑治疗新生儿上消化道出血的临床效果。方法 :对2013年1月~2014年2月期间我院收治的68例上消化道出血新生儿的临床资料进行回顾性研究。我们将这68例患儿随机分为观察组和对照组,每组各有34例患儿。我院给对照组患儿使用止血敏和维生素K1进行治疗,给观察组患儿在使用止血敏和维生素K1(用法均与对照组患儿相同)的基础上,加用奥美拉唑进行治疗。治疗结束后,比较两组患儿治疗的效果。结果 :观察组患儿治疗的总有效率为97.06%。对照组患儿治疗的总有效率为85.29%。观察组患儿治疗的总有效率明显高于对照组患儿,二者相比差异具有显著性(P<0.05)。结论 :用奥美拉唑治疗新生儿上消化道出血的效果显著。此药可作为临床上治疗新生儿上消化道出血的优选药物。

Objective: To probe into the clinical effects of the hemorrhage newborn upper digestive tract treated with omeprazole. Methods: 68 newborns patients who suffered from hemorrhage of upper digestive tract and who accepted treatment in our hospital from January 2013 to February 2014 were taken as the research objects, and these patients were randomly divided into the control group, with 34 patients in each group. In the control group, they were treated with the routine curing while in the observation group, on the basis of the treatment in the control group, they were treated with the omeprazole. Then, the clinical effects of these two groups of patients were compared. Outcome: The response rate in the observation group was 97.06%, and were higher than that in the control group was 85.29%, and the differences had the statistical significance(P<0.05). Conclusion: The clinical effects of the hemorrhage newborn upper digestive tract treated with omeprazole are good enough, which can stop bleeding effects, thus should be promoted in the clinical application.