联用左卡尼汀和透析疗法治疗尿毒症的效果研究

Study on the effect of levocarnitine combined with uremia and dialysis therapy…

目的:探讨联合使用左卡尼汀和透析疗法治疗尿毒症的临床效果。方法 :对2013年1月~2015年1月期间我院收治的80例尿毒症患者的临床资料进行回顾性研究。我们将这80例患者随机分为观察组和对照组,每组各有40例患者。我院使用透析疗法对对照组患者进行治疗,联合使用左卡尼汀和透析疗法(方法与对照组患者相同)对观察组患者进行治疗。治疗结束后,比较两组患者治疗前后白蛋白的水平、总蛋白的水平、前白蛋白的水平和转铁蛋白的水平。结果 :在治疗前,两组患者白蛋白的水平、总蛋白的水平、前白蛋白的水平和转铁蛋白的水平相比无显著性差异(P>0.05)。在治疗后,两组患者白蛋白的水平、总蛋白的水平、前白蛋白的水平和转铁蛋白的水平均较治疗前有明显的提高,其中观察组患者治疗后白蛋白的水平、总蛋白的水平、前白蛋白的水平和转铁蛋白的水平均明显高于对照组患者,二者相比差异具有显著性(P<0.05)。结论 :联合使用左卡尼汀和透析疗法治疗尿毒症的效果确切,可有效地提高患者体内蛋白质的水平,改善其营养状况。此联合疗法可作为临床上治疗尿毒症的优选方法。

objective: to study the l-carnitine the clinical value of uremia patients treated with dialysis; Methods: from January 2013 to January 2015 were treated 80 cases of patients with uremia, which each 40 patients randomly divided into experimental group and control group, control group patients give regular hemodialysis treatment, the experimental group to cooperate l-carnitine blood dialysis patients, the clinical therapeutic effect of two groups of patients were analyzed; Results: after treatment, the indices such as serum albumin, total protein of the experimental group patients significantly better than the before treatment, and patients is significantly higher than control group, compare the difference was statistically significant(P < 0.05). Conclusion: in treatment of patients with uremia, application of l-carnitine can cooperate with dialysis treatment of anemia in patients with conditions and effectively improve the nutritional status, has the high security, hemodialysis can more effectively.