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浅论老年慢性肾脏病患者肾功能损伤与外周动脉病变的相关性

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摘要 目的:探讨老年慢性肾脏病(CKD)患者肾功能损伤与外周动脉病变(PAD)的相关性。方法 :对2012年5月~2014年5月期间我院收治的493例老年CKD患者的临床资料进行回顾性研究。我院通过对这些患者的尿微量白蛋白水平、肾小球滤过率(GFR)及踝肱比(ABI)进行检测,分析并总结老年CKD患者肾功能损伤与PAD的相关性。结果 :老年CKD患者的GFR越低,其发生PAD的危险度越高。无微量白蛋白尿且GFR≥60ml/min per1.73m2的患者其ABI<0.9(PAD)的发生率为8.97%,无微量白蛋白尿且GFR<60ml/min per1.73m2的患者其ABI<0.9(PAD)的发生率为15.09%,有微量白蛋白尿且GFR≥60ml/min per1.73m2的患者其ABI<0.9(PAD)的发生率为20.69%,有微量白蛋白尿且GFR<60ml/min per1.73m2的患者其ABI<0.9(PAD)的发生率为26.67%。有微量白蛋白尿的患者其ABI<0.9(PAD)的发生率明显高于无微量白蛋白尿的患者,差异显著(P<0.05),具有统计学意义。有微量白蛋白尿且GFR<60ml/min per1.73m2的患者其ABI<0.9(PAD)的发生率最高,差异显著(P<0.05),具有统计学意义。结论 :当老年CKD患者出现肾功能损伤时,其发生PAD的几率明显增加。因此,临床上应加强对出现肾功能损伤的老年CKD患者进行治疗,以降低其PAD的发生率。
出处 《当代医药论丛》 2015年第21期243-244,共2页
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