乙酰水杨酸印迹微球的制备及吸附性能

Preparation of Acetosalicylic Acid Molecularly Imprinted Polymeric Microspheres and Their Adsorption Properties

以乙酰水杨酸为模板分子,偶氮二异丁腈作为引发剂,丙烯酰胺作为功能单体,采用自组装体系分子印迹法制备出对乙酰水杨酸有特异识别性和性能稳定的印迹聚合物微球(MIP).优化制备分子印迹聚合物微球的条件,采用红外光谱及扫描电镜表征印迹微球的化学结构和表面形貌,对MIP的吸附性能及选择吸附性能进行研究.结果表明,模板分子、功能单体与交联剂的最佳配比为1∶4∶20,最佳反应时间为48h,所制备的MIP粒径均一,球形度好,性能稳定,并且对模板分子有特异的识别能力,最大表观结合量27.96mg/g.

Acetosalicylicacid(Asp)molecularly imprinted polymeric microspheres were prepared by selfassembly polymerization in acetonitrile,when acetosalicylicacid was used as template molecules,azobisisobutyronitrile as polymerization initiator and acrylamide as functional monomer.Their polymerization conditions were discussed,meanwhile.The acetosalicylic acid molecular imprinted polymeric microspheres(MIPs)had specific selectivity of Asp.The structure,surface and heat stability of MIPs were characterized.The results showed that the reaction conditions were n(Asp)∶n(AM)∶n(EDMA)=1∶4∶20,optimum reaction time was 48 hand the maximum adsorption capacity of theimprinted microspheres for Asp was up to 27.96 mg/g.The MIPs had reorganization of acetosalicylic acid molecules.