可溶性P-选择素与急性冠状动脉综合征的关联性被引量：8

The relationship between serum soluble P-selectin levels and acute coronary syndrome

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摘要目的 :观察急性冠状动脉综合征与血清中可溶性 P-选择素的关联性。方法 :采用 EL ISA法检测 32例不稳定型心绞痛 (U A)、47例急性心肌梗死 (AMI)、30例稳定型心绞痛 (SA)患者和 40例健康者 (对照组 )血清可溶性 P-选择素水平。结果 :对照组和 SA组分别为 132 1± 12 1ng· L- 1和 15 2 0± 113ng· L- 1 ,而 U A组和 AMI组可溶性P-选择素明显升高 (分别为 76 45± 95 0 ng· L- 1和 46 6 5± 44 4ng· L- 1 ,P<0 .0 5 )。结论 :可溶性 P-选择素与急性冠状动脉综合征有关联。 AIM:To investigate the relationship between serum soluble P-selectin levels and acute coronary syndrome. METHODS:The levels of serum soluble P-selectin were determined by enzyme-linked immunosorbent assay in 32 unstable angina(UA)cases, 47 acute myocardial infarction(AMI)cases, 30 stable angina(SA)cases and 40 healthy cases as control. RESULTS: Compared with the healthy control cases (1321±121 ng·L -1) and SA cases (1520±113 ng·L -1), the levels of soluble P-selectin increased significantly in the AMI cases and UA cases (7645±950 ng·L -1 and 4665±444 ng·L -1, P<0.05, respectively). CONCLUSION:The increased soluble P-selectin levels is related to the formation and progression of acute coronary syndrome.

作者陈浩李源王晓明

机构地区武警西藏总队医院内科第四军医大学西京医院老年病科

出处《心脏杂志》 CAS 2003年第4期326-327,330,共3页 Chinese Heart Journal

基金陕西省科学技术研究发展计划项目 2 0 0 1K10 -G7(2 )

关键词冠状动脉疾病急性冠脉综合征 P-选择素 coronary disease acute coronary syndrome P-selectin

分类号 R541.4 [医药卫生—心血管疾病]

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参考文献6

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