慢性阻塞性肺病患者食物生热效应的研究

Study on the Thermic Effect of Food of Patients With Chronic Obstructive Pulmonary Disease

目的 研究慢性阻塞性肺病 (COPD)食物生热效应 (TEF)的变化及其临床意义。方法 运用开放式间接能量测定仪 ,用头罩法测定 12例男性COPD基础能量消耗 (BEE) ,测定 11例男性COPD静息能量消耗 (REE) ,两组患者性别、年龄、身高、体重均无显著差别 (P >0 0 5 ) ,即TEF =REE -BEE。结果 发现BEE和REE实测值分别为 ( 1114± 2 0 8)kcal/d ,( 14 3 3± 13 6)kcal/d ,REE实测值比BEE增加了 2 8%。结论 COPD患者TEF的能耗显著增加 。

Objective To study on the thermic effect of food (TEF) of patients with chronic obstructive pulmonary disease(COPD).Methods Basal energy expenditure (BEE) of 12 male cases and resting energy expenditure (REE) of 11 male cases of COPD were detected by indirect calorimetry with metabolic cart. There were no significant difference in sex, age, height and body weight between two groups' e.g:TEF=REE-BEE.Results BEE and REE were 1114±208kcal/d,1433±136kcal/d respectively, the latter was higher 28% than BEE.Conclusion TEF increases significantly which may contributes to malnutrition and non-response to nutritional support in patients with COPD.