肠吸收促进剂的研究进展

Development of Intestinal Absorption Enhancers

肠吸收促进剂可改善肠粘膜透过能力低药物的口服生物利用度。本文综述了肠吸收促进剂研究的实验方法、制剂及生理因素对其促吸收作用的影响、安全性问题以及近年重点研究的促进剂类型。

Intestinal absorption enhancers are used to improve oral bioavailability of those compounds with poor membrane permeability. The experiments, formulation, physiologic variables and toxicity problem are reviewed to exemplify the use of several absorption enhancers.