摘要
N-Methylmorpholine was synthesized by alkylation of morpholine with chloromethane in sodium hydroxide solution. The influences of reaction temperature, reaction time and molar ratio of reactants on the yield of the reaction were examined. The optimum reaction conditions are as follows: reaction temperature 35 ℃, time 5 h, n(morpholine)∶n(monochloromethane)=1∶1.1, n(morpholine)∶n(sodium hydroxide)= 1∶1.2, yield of N-methylmorpholine 85%, purity 98%.
N-Methylmorpholine was synthesized by alkylation of morpholine with chloromethane in sodium hydroxide solution. The influences of reaction temperature, reaction time and molar ratio of reactants on the yield of the reaction were examined. The optimum reaction conditions are as follows: reaction temperature 35 ℃, time 5 h, n(morpholine)∶n(monochloromethane)=1∶1.1, n(morpholine)∶n(sodium hydroxide)= 1∶1.2, yield of N-methylmorpholine 85%, purity 98%.
出处
《应用化学》
CAS
CSCD
北大核心
2003年第9期917-918,共2页
Chinese Journal of Applied Chemistry
基金
安阳市科委 2 0 0 0年资助项目 ( 2 0 0 0 64 )
关键词
N-甲基吗啉
合成
一氯甲烷
N-methylmorpholine,synthesis,monochloromethane
