ADENOSINE REDUCES INTRAOCULAR PRESSURE AND INCREASES OPTIC NERVE HEAD AND CHOROIDAL BLOOD FLOW IN HEALTHY HUMANS

Purpose: There is evidence from a variety of animal studies that the adenosine system plays a role in the control of intraocular pressure (IOP) and ocular blood flow. However, human data on the effect of adenosine on IOP, choroidal and optic nerve blood flow are lacking. Methods: We investigated the effect of stepwise increasing doses of adenosine (10, 20, 40μg/kg/min, 30 min-