INTRA-OCULAR PRESSURE CHANGES AF-TER B-BLOCKER EYE DROPS INSTILLA-TION AND BICYCLE ERGOMETER EXER-CISE

Purpose: To evaluate the additive IOP effect of physical aerobic exercise (bicycle ergometer), in healthy individuals, after the in- stillation of b-blockers. Material: 20 healthy individuals. Methods: The IOP was measured before and 2 hours after the instillation of eye drops (b-blockers) in the right eye (OD) of the individuals.. The IOP was measured again within 5 minutes after the completion of physical exercise on a bicycle ergometer (about 10 minutes of duration - till exhaustion). Results: The instillation of b-blocker eye drops in the right eye was followed by an IOP decrease after 2 hours. The IOP decreased further more after the performance of the bicycle ergometer exercise. Mean IOP before the instillation of b-blocker. right eyes: 16.25, left eyes: 16.15. Mean IOP after the instillation of b-blocker. right eyes: 12.35 (decrease ranged from 3 to 5 mm Hg), left eyes: 14.20.. The IOP lowering effect after the bicycle ergometer exercise for the right eyes ranged from 1 to 5 mmHg. Mean IOP 10.20.

Purpose: To evaluate the additive IOP effect of physical aerobic exercise (bicycle ergometer), in healthy individuals, after the in- stillation of b-blockers. Material: 20 healthy individuals. Methods: The IOP was measured before and 2 hours after the instillation of eye drops (b-blockers) in the right eye (OD) of the individuals.. The IOP was measured again within 5 minutes after the completion of physical exercise on a bicycle ergometer (about 10 minutes of duration - till exhaustion). Results: The instillation of b-blocker eye drops in the right eye was followed by an IOP decrease after 2 hours. The IOP decreased further more after the performance of the bicycle ergometer exercise. Mean IOP before the instillation of b-blocker. right eyes: 16.25, left eyes: 16.15. Mean IOP after the instillation of b-blocker. right eyes: 12.35 (decrease ranged from 3 to 5 mm Hg), left eyes: 14.20.. The IOP lowering effect after the bicycle ergometer exercise for the right eyes ranged from 1 to 5 mmHg. Mean IOP 10.20. As regards the left eye (without b-blocker medication) the IOP lowering effect of the bicycle ergometer exercise ranged from 1 to 5 mmHg. Mean IOP 12.50. Conclusions: The instillation of b-blockers has an IOP lowering effect in healthy individuals. The IOP decreases further more after the physical aerobic exercise (bicycle ergome-ter). The potential mechanism of the IOP decrease after a physical aerobic exercise was extensively discussed in various studies and remains under investigation. The present study is indicative that the b-sympathetic blockade does not exclude the influence of the exercise induced IOP lowering effect