复合生物陶瓷人工骨与骨组织结合界面扫描电镜观察及X线能谱分析

The Study of the Interfaces between Compound Bioceramics Artificial Bone and Bone By Means of Scanning Electron Microscope and X-ray Energy Spectrum Analysis

本实验选用自行研制的复合生物陶瓷(简称CBC)植入4只成年杂种狗的下颌骨体部人造骨缺损处。术后3月处死动物获取标本,在组织学观察的同时,取部份标本经处理后用扫描电镜和X线能谱仪对该材料与骨组织结合界面进行观察研究、结果表明复合生物陶瓷与骨组织呈直线骨性结合。关于其结合机理,经分析认为可能与离子交换后Ca,P聚集界面和磷酸盐物质扩散沉积于界面有关。

The Compound Bioceramic (CBC),a newly developed artificial bone material,were im- planted in the man-made defects on madibular bodies of four dogs.The an imals were sacri- ficed three months later.The specimens were prepared by routine procedures.The interfaces between the CBC materials and bones were studied by electromicroscope scanning and X-ray energy spectrum analysis:the results showed that the CBC materials could be bioconnected with bones (osseous bond as was called).The study suggested that the osseous bond mecha- nism of the CBC material be related to the ion migration and deposition of calcium and phosphate on the interfaces.