2016例高原肺水肿现场救治体会

THE CLINICAL ANALYSIS FOR THE TREATMENT OF 2 016 CASES WITH HIGH ALTITUDE PULMONARY EDEMA

目的 :寻找现场有效救治高原肺水肿的方法和措施 ;方法 :采用系统回顾性方法 ,分析我院自 1 956年— 2 0 0 2年收治的高原肺水肿住院病例 ;结果 :氨茶碱组、速尿组、硝苯吡啶组、酚妥拉明组、654 -2组、高压氧组及NO组患者症状、体征、X线平片肺部阴影消失时间与基础治疗组比较 ,差异有显著性 ;地塞米松组同基础治疗组相比无统计学意义 ;各治疗组相比 ,氨茶碱组、NO组及速尿组的临床疗效明显优于其它治疗组 ;结论 :综合比较各种药物、措施 ,现场救治HAPE临床疗效的优劣依次为 :氨茶碱、NO、速尿、硝苯吡啶、酚妥拉明、高压氧等。

Objective:To find the useful methods for the treatment of high altitude pulmonary edema(HAPE) at high altitude.Methods:The 2 016 cases with HAPE in our hospital from 1956-2002 were analyzed retrospectively.Results:Compared with basic therapy,the average admitted days were reduced,the symptom,physical and X-ray signs disappeared more quickly in aminophylline,furosemide,nifedipine,phentolamine,anisodamine(654-2),hyperbaric oxygen and nitric oxide therapy.The therapeutic effect of dexamethasone in HAPE was as same as the basic therapy.Conclusion:In general,the clinical effects of aminophylline,furosemide and NO in patients with HAPE were better than the effects of nifedipine,phentolamine,anisodamine and hyperbaric oxygen.