催产素联合米索前列醇减少产后出血150例分析

Analysis on the efficacy of oxytocin combining misoprostol in reducing postpartum blood loss

目的 探讨催产素联合米索前列醇用以减少产后出血的治疗效果和安全性。方法 选择住院分娩的足月妊娠、单胎头位初产妇 3 0 0例 ,随机分为两组 ,在分娩第二产程常规肌注催产素 2 0u ,观察组 15 0例于胎盘娩出后予直肠放置米索前列醇40 0 μg ,对照组 15 0例不作任何处理。观察两组在胎盘娩出时的出血量及胎盘娩出至产后 2h出血量的比较。 结果 观察组在胎盘娩出时出血量 ,胎盘娩出至产后 2h出血量以及产后总出血量明显减少 ,两组有显著差异 (P <0 .0 5 )。结论 治疗量米索前列醇用于预防和治疗产后出血是安全的、有效的 。

Objective To study the efficacy and safety of oxytocin combining misoprostol in reducing postpartum blood loss.Methods Three hundred primipara with term singleton pregnancy and spontaneous delivery were enrolled. Twenty U Oxytocin were injected intravenously in the second stage of labor. Then all the cases were randomly assigned to two groups. Observation group:150 cases were placed 400μg misoprostol in recta after the delivery of placenta. Control group:150 cases were received no treatment.The amounts of vaginal bleeding were observed immediatelyafter the delivery of placenta and till two hours later. Results The amounts of vaginal bleeding after the delivery of placenta were not significant in both groups (P>0.05).After the delivery of placenta two hours later,the amounts of vaginal bleeding in observation group were significantly less than in control group (P<0.05).Conclusion Treatment dose misoprostol was efficient and safe in reducing postpartum blood loss, combined treatment can reduce postpartum blood loss significantly.