摘要
以邻氯苄氯、对羟基苯乙酮、三氮唑为主要原料 ,通过 O-烷基化、溴化、缩合及N-烷基化反应合成了 4- [4-甲基 - 2 - ( 1 H- 1 ,2 ,4-三唑 - 1 -基 -甲基 ) - 1 ,3-二氧戊环 - 2 -基 ]-苯基 - 2 -氯苯基醚。采用 IR、1H- NMR、EA和 MS手段对其结构进行了验证。初步生物活性测试表明 ,该化合物具有较好的杀菌活性和一定的植物生长调节活性。
methyl 2 (1H 1,2,4 triazol 1 yl methyl) 1,3 dioxlan 2 yl] phenyl 2 chlorophenyl ether was synthesized through O alkylation, bromination, condensation and N alkylation using O chlorobenzyl chloride, p hydroxyacetophenone and triazole as starting materials. Its structure was confirmed by 1H NMR,IR,MS and elemental analysis.Preliminary biological test showed that the synthesized compound exhibited stronger fungicidal activity and some plant growth regulating activity.
出处
《青岛科技大学学报(自然科学版)》
CAS
2003年第4期309-311,共3页
Journal of Qingdao University of Science and Technology:Natural Science Edition