米索前列醇氧化亚氮用于人工流产术临床研究

Clincal study on the effect of misoprostol and inhaling nitrous oxide on artificial abortion

目的 探讨米索前列醇、氧化亚氮用于人工流产的临床效果。方法 将行人工流产的妇女 180例随机分米索前列醇组、氧化亚氮组、米索前列醇氧化亚氮组 ,每组 6 0例。分别观察镇痛效果、宫颈扩张情况、手术时间、术中出血及不良反应。结果 镇痛效果 :氧化亚氮组、米索前列醇氧化亚氮组与单用米索前列醇组相比差异有非常显著意义 (P <0 0 1)。宫颈扩张情况 :米索前列醇组、米索前列醇氧化亚氮组与单用氧化亚氮组相比差异有非常显著意义 (P <0 0 1)。术中出血、手术时间三组相比差异无显著意义。结论 米索前列醇和氧化亚氮联合用于人工流产 ,既可实现无痛人流又可达到良好的宫颈扩张效果 ,值得推广应用。

Objective To study the effect of misoprostol and inhaling nitrous oxide on artificial abortion.Methods 180 women opting for voluntary artificial abortion were randomly divided into three groups treated with misoprostol,inhaling nitrous oxide,and misoprostol combined with inhaling nitrous oxide respectively.The pain degree,the bleeding volume,the facility and the time of the operation and the side effect were observed during the operation.Results The analgesia effect was much better in the groups with nitrous oxide than that without nitrous oxide(P<0.01).The cervical dilatation was significantly easier in the groups with misoprostol than that without misoprostol(P<0.01).The bleeding volume and the time of the operation were similar in all three groups.Conclusion Vaginal misoprostol combined with inhaling nitrous oxide used for artificial abortion was most effective and worthy popularizing.