卡维地洛在运动诱发和动态心电图监测时对心肌缺血的影响

Effects of corvedilol on treadmill exercise test(TET) and 24-hour Holter with myocardial ischemia

目的 观察卡维地洛与非洛地平治疗在运动诱发和动态心电图监测时对心肌缺血的影响。方法 对 110例活动平板运动试验与动态心电图监测有心肌缺血的病人分为两组 ,分别服用卡维地洛和非洛地平 4周 ,观察治疗后效果。结果 两组均可提高抗心肌缺血效应和增加病人运动耐量 ,但卡维地洛提高病人运动耐量时间明显优于非洛地平 (P <0 0 5 )。结论 卡维地洛可提高抗心肌缺血效应 ,安全性好。

Objective To observe the effects of carvedilol and felodipine on treadmill exercise test(TET) and 24 hour Holter with myocardial ischemia.Methods The 110 patients with myocardial ischemia in treadmill exercise test and 24 hour Holter were divided into two groups and treated with carvedilol(60 patients) and felodipine(50 patients) for 4 weeks.The curative effect were observed and compared.Results The anti ischemic efficacy and total exercise time were increased in two groups,but the total exercise time were prolonged remarkably in carvedilol group(P<0.05).Conclusion Carvedilol may increase the effect of anti ischemic and ensures safety.