组织内化疗结合电化学治疗原发性巨块型肝癌的临床观察

Clinic observation on the Primary giant liver cancer treated with the combing methods of innertissue chemical and electrochemical therapy

目的 观察对原发性巨块型肝癌组织内化疗结合电化学疗法疗效。方法 观察组肝癌患者开腹后 ,肿块组织内注入阿霉素 ,再用电化学治疗 ;对照组为肝动脉介入栓塞化疗。结果 观察组 32例 ,近期有效率 84 38% ,与对照组 (39例 ,近期有效率 6 9 2 3% )相比差异显著 (P >0 .0 5 )。两年中位生存期 15 1月 ,与对照组 (14 7月 )的差异不显著 (P >0 0 5 )。结论 原发性巨块型肝癌组织内化疗结合电化学疗法具有较好的短期缓解率 ,且副作用小 ,费用低 ,术后恢复快 ,不失为一种姑息性治疗晚期肝癌的方法 。

Objective The primary giant liver cancer was treated withcombing methods of innertissue chemical and electrochemical therapy.The short-time curative effects and the two year middle live perild were observed.Methods After opening the abdomen of patient with liver cancer in observing group,Adriamycin(ADM)was injected into the tumour tissue,then using the electrochemical therapy.The hepa-artery interpose embolism chemical therapy was employed in the comtrol group.Results The 32 cases in observing group have 84.38% of short-time curative effects which significntly higher than the control group (39 cases,69,23% of short-time curative effects)(p<0.05),and there had no significant difference(p>0.05) of the two year middle live period between observing group (15.1 months) and conrtol group(14.7 months).Conclusion The combing methods of innertissue chemical and electrochemical therapy for primary giant liver cancer have a better short-time curativer effects,less by-effect,Iower cost and quick recover after operation.These is a palliative treatment for Iater period liver cancer.