海口市儿童幽门螺杆菌感染的流行病学研究

Epidemiological study on infectious status of helicobacter pylori in children in Haikou City

目的 了解海口市儿童幽门螺杆菌 (H·pylori以下简称Hp)感染率 ,探讨社会经济条件等因素对Hp流行的影响 ;Hp的感染途径及其致病性 ,为在儿童期是否作Hp的防治提供科学依据。 方法 采用胃幽门螺杆菌抗体检测试剂盒 ,对海口市 10 0 0名 3月～ 14岁儿童进行HpIgG抗体检测并作分析。 结果 ①海口市儿童Hp平均感染率为 2 5 6% ,且随着年龄的增加有递增趋势 ,13～ 14岁的儿童感染率为 3 7 4% ;②生活环境好的Hp感染率 ( 13 5 7% )与生活环境差的感染率 ( 3 3 17% )比较 ,家庭收入高的Hp感染率 ( 15 2 0 % )与低收入的感染率 ( 3 8 76% )比较差异均显著 ;③有胃十二指肠疾病者Hp的感染率高达 75 0 %。 结论 ①海口市儿童存在较高的Hp感染率 ,且随着年龄的增加递增。②环境因素和家庭经济收入与Hp感染率之间存在负相关。③Hp感染存在家庭聚集现象 ,存在人—人传播的可能性。④并非Hp感染均致病 。

Objective To investigate the prevalence of Halicobacter pylori (H·pylori) infection among children and possible relationship between the socioeconomic status of their families and the prevalence Method Serum H·pylori-IgG antibodies of 1000 children 3morths～14 years of age were measured by kit of Shan Qiang campany Results ①Mean Prevalence of H·pylori was 25 60% 13～14year of age was 37 40% ②H pylori infection in finest environment (13 75%), H pylori infection highest income (15 20%), H pylori infection in worst environment (33 17%), H pylori infection lowest income (38 76%)was very difference ③H pylori infection of stomach and duodenum disease was 75 0% Conclusion ①Prevalence of H·pylori among in Hai-kou child was high and it increased with age ②There was an inverse correlation between the infection rate and the level of socioeconmic status ③H pylori infection had familial clustering It was possible spread over the peple ④H pylori infection does not all cause illnes It will be necessary research for popular of element