温岭市878名高一学生HBV感染状况调查分析

Investigation into the infectious status of HBV in 878 senior middle school students.

目的 研究HBV在学生中感染状况 ,掌握乙肝在学生中的发生与流行规律 ,为乙肝防治工作提供依据。 方法 对某中学高一年级 878名新生采取静脉血液 ,采用ELISA进行HBV五项血清学标志物检测。 结果 抗 -HBs阳性率最高 ,占 76 76% ;其次抗 -HBc阳性率为 15 95 % ;HBsAg阳性率为 8 66% ;抗 -HBe阳性率为 8 5 7% ;HBeAg阳性率 2 73 % ;并且发现中学生中HBV感染者除抗 -HBs阳性外 ,以“HBsAg、HBeAg、抗 -HBc”阳性和“HBsAg、抗 -HBc、抗 -HBe”阳性两种感染模式为常见 ,二者合计为 6 49%。 结论 由于乙肝疫苗的接种和国家、学校重视学生管理等原因 ,目前中学生HBV感染率已有所下降 ,在HBV感染者中男生感染率显著高于女生 ,并且以“大三阳”和“小三阳”

Objective To understand the infectious status of hepatitis B virus (HBV) in the senior middle school students and the prevalent features provide scientific basis for conducting control work Methods Venous blood was taken from 878 senior middle school students and five serological markers of HBV were determined by ELISA Results The anti-HBs positive rate was the highest, accounting for 76 76%, followed by anti-HBc 15 95%, HBsAg positive rate 8 66%, anti-HBe positive rate 8 57% and HBeAg positive rate 2 73% Two infectious models were common observed in the students, namely HBsAg, HBeAg and anti-HBc positives, HBsAg, Anti-HBc an Anti-HBe positives The infectious rate in the males was significantly higher than that in the females Conclusion The infectious rate of HBV in the middle school students has been reduced due to the implementation of vaccination and the prevention and control activities jointly made by the Government and the school authority Measures be taken and efforts still be made for the control of HBV infection in middle school students