原发性肝癌血行转移影响因素的临床研究

CLINICAL STUDY OF RISK FACTORS IN INTRAVENOUS METASTASIS OF PRIMARY HEPATOCARCINOMA

目的 :了解原发性肝癌 (PHC)血行转移的影响因素及转移规律。方法 :对 110例PHC患者 ,分析PHC大小、部位和数量以及AFP、HBV、AKP、r-GT与血行转移的关系。结果 :男性PHC患者血行转移率高于女性患者 (P <0 .0 5 ) ;老年人PHC患者血行转移率低于中青年患者 (P <0 .0 5 ) ;左右肝同时受累者血行转移率高于左右肝单独受累者 (P <0 .0 5 ) ;小肝癌转移率高于非小肝癌 (P <0 .0 5 ) ;HBV感染阳性PHC患者血行转移率高于HBV感染阴性患者 (P <0 .0 5 )。结论 :男性、中青年患者、左右肝同时受累者、小肝癌及HBV感染阳性PHC患者容易发生血管内转移。

Objective:To illustrate the risk factors and principle of hematogenous metastasis of primary hepatocarcinoma (PHC).Methods:We investigated 110 cases of PHC in the present study. The participation of the size, site, quantity of the masses and AFP, HBV infection, AKP, r-GT in the hematogenous metastasis of PHC was evaluated.Results:The rate of hematogenous metastasis was higher in the male PHC while lower in the senile PHC. The rate of hematogenous metastasis was much higher in those both right and left liver lobe suffered, small hepatocarcinoma and HBV infected.Conclusions:Hematogenous metastasis occurs more easily in senile,male PHC and those both right and left liver lobe suffered, small hepatocarcinoma and HBV infected.