期刊文献+

静脉用地尔硫卓对难治性不稳定型心绞痛的疗效观察 被引量:13

Clinical Observation of Intravenous Diltiazem in Treatment for Patients with Unstable Angina Pectoris
下载PDF
导出
摘要 目的 :观察静脉用地尔硫卓对难治性不稳定型心绞痛 (UAP)患者的短期疗效、安全性及不良反应。方法 :选择 32例难治性UAP患者 ,静脉注射地尔硫卓 10mg后 ,继以 3~ 15mg静脉点滴维持 4 8h(对入选时心绞痛未发作者直接给予持续静脉滴注 ) ,观察心绞痛症状、心电图及血压、心率变化。结果 :32例UAP患者开始用药后 4 8h内与用药前 4 8h比较 ,平均心绞痛发作次数减少 ,平均心绞痛最长持续时间缩短 ,其中 16例患者在用药开始后 4 8h内未再发作心绞痛 ;治疗后 2 4h和 4 8h心电图缺血性表现明显改善 ;血压下降 ,心率减慢 ,心肌耗氧量指标降低 ;出现 1例窦性心动过缓、1例低血压、1例头痛和 1例胃肠道反应 ,经处理后均恢复。结论 :短期静脉用地尔硫卓是一项缓解难治性UAP患者症状、改善心肌缺血的安全而有效措施。
出处 《中国现代医学杂志》 CAS CSCD 2003年第12期87-88,共2页 China Journal of Modern Medicine
  • 相关文献

参考文献3

二级参考文献19

  • 1ANTMAN EM, TANASIJEVIC MJ, THOMPSON B, et al. Cardiac-specific troponin I levels to predict the risk of mortality in patients with acute coronary syndromes [J]. N Engl J Med, 1996, 335(18): 1342-1349.
  • 2OHMAN EM, ARMSTRONG PW, CHRISTENSON RH, et al. Cardiac troponin T levels for risk stratification in acute myocardial ischemia [J]. N Engl J Med, 1996, 335 (18):1333-1341.
  • 3HAMM CW, GOLDMANN BU, HEESCHEN C, et al. Emergency room triage of patients with acute chest pain by means of rapid testing for cardiac troponin T or troponin I [J]. N Engl J Med, 1997, 337 (23): 1648-1653.
  • 4STUBBS P, COLLINSON P, MOSELEY D, et al. Prospective study of the role of cardiac troponin T in patients admitted with unstable angina [J]. Br Med J, 1996, 313 (7052): 262-264.
  • 5ANTMAN EM, FOX KM. Guidelines for the diagnosis and management of unstable angina and non-Q-wave myocardial infarction: proposed revisions [J]. Am Heart J, 2000, 139(3):461-475.
  • 6COHEN M, DEMERS C, GURFINKEL EP, et al. A comparison of low-molecular-weight heparin with unfractionated heparin for unstable coronary artery disease [J]. N Engl J Med, 1997, 337(7):447-452.
  • 7ANTMAN EM, MCCABE CH, GUEFINKEL EP, et al. Enoxaparin prevents death and cardiac ischemic events in unstable angina/non-Q-wave myocardial infarction: results of the Thrombolysis in Myocardial Infarction (TIMI) ⅡB trial [J]. Circulation, 1999, 100 (15):1593-1601.
  • 8GURFINKEL EP, MANOS EJ, MEJAIL RI, et al. Low molecular weight heparin versus regular heparin or aspirin in the treatment of unstable angina and silent ischemia [J]. J Am Coll Cardial, 1995, 26(2):313-318.
  • 9OASIS-2 investigators. Effects of recombinant hirudin (lepirudin) compared with heparin on death, myocardial infarction, refractory angina, and revascularisation procedures in patients with acute myocardial ischaemia without ST elevation: a randomised trial [J]. Lancet, 1999, 353 (9151): 429-438.
  • 10LEAN MB, BAIM DS, POPMA JJ, et al. A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting [J]. N Engl J med, 1998, 339(23): 1665-1671.

共引文献69

同被引文献39

引证文献13

二级引证文献34

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部