冠状动脉造影正常的急性心肌梗死患者的临床特征

Clinical analysis of normal coronary arteriography with acute myocardial infarction

目的 :对比观察急性心肌梗死 (AMI)冠状动脉 (冠脉 )冠脉造影正常和异常患者临床及血管造影特点。方法 :回顾分析 1997年 6月～ 2 0 0 2年 12月 318例AMI患者的临床特征及血管造影结果。结果 :318例AMI患者中冠脉正常者 2 6例占 8 2 %,多为男性 ,年龄较轻 ,发病前有大量吸烟、高度紧张及劳累等明确诱因 ,多无心绞痛史、高血压病史、糖尿病史及血脂异常者史。结论 :AMI可发生于冠脉正常的患者中 ,多为年龄较轻男性 ,一般都有明确的吸烟等诱因 ,冠脉痉挛和急性血栓形成伴自溶可能是其主要发病机制。

Object To observe clinical and angiographic features of acute myocardial infarction (AMI) with normal and annormal coronary angiogram (CAG).Methods Clinical characteristics and the results of CAG in 318 patients with AMI enrolled from June 1997 to December 2002 were analysed.Results The patients with AMI and normal CAG accounted for 26/315(8.2%),most of whom were more males and more younger,most of patieats had inducement as heavy cigarette smocking and/or strenuous exertional working,and free of angina pectoris,hypertension,diabetes mellitus and hyperlipidemia (P<0.05).Conclusion AMI might be happened in patients with normal coronary arteries and most of them were younger males and had inducement as smocking.coronary artery spasm and acute thrombosis and auto-thromobsis are chief mechanism.