卢戈氏液染色在食管癌诊断及治疗中的作用探讨

Significance of Lugol′s Staining in Diagnosis and Treatment of Esophageal Cancer

目的 探讨卢戈氏液染色法在食管癌诊断及治疗中的临床意义。方法 对 90例手术切除的新鲜食管癌组标本应用卢戈氏液进行染色 ,并对原发肿瘤及淡染区进行病理组织学检查。结果 食管黏膜单纯性增生 11处 ,轻中度不典型增生 3 3处 ,重度不典型增生 2 4处 ,早期癌 18处。结论 卢戈氏液染色法操作简便、快捷 ,可结合食管镜检查对早期癌灶进行识别和定位 ;术中对已切除的食管癌标本进行染色观察 ,可协助判断食管切缘是否有癌组织残留 ;

Objective To evaluate the significance of Lugol′s staining in diagnosis and treatment of esophageal cancer.Methods 90 surgically resected specimens of esophageal cancer were examined by Lugol′s iodine staining and were studied by histopathology.Results There were 83 specimens unstainted by Lugol′s iodine,including 11 simple squamous epithelial hyperplasia,33 mild-moderate squamous epithelial dysplasia,24 severve squamous epithelial dysplasia and 18 early esophageal cancer.Conclusion Lugol′s iodine staining is simple and fast.It is feasible to detect early esophageal cancer by endoscopy and evaluate the residual tissue of incisal margin of esophageal cancer in operation.A sufficient resected length is necessary for cases with the intermediate stage and advanced cancer.