脑梗死后智能障碍影响因素分析

A Study on The Effect Factors of Intelligence Impairment in Cerebral Infarct Patients

目的 探讨影响脑梗死后智能障碍的因素。 方法 应用长谷川痴呆量表对 2 49例经 CT证实的脑梗死患者进行智能测评 ,评分 0～ 2 1 .5为智能障碍组 ,2 2～ 3 2 .5为正常组 ,探讨智能障碍的发生与性别、年龄、文化程度、卒中主要危险因素 (高血压和糖尿病 )、梗死灶数量及体积 ,以及脑萎缩和脑白质疏松之间的相互关系。 结果 2 49例脑梗死患者中有 1 0 6例 (4 2 .6% )出现智能障碍。并发现年龄、性别、文化程度、高血压病、糖尿病与智能障碍的发生有关 ;梗死灶的数量越多、体积越大其智能障碍发生率越高 ;脑萎缩及脑白质疏松与智能障碍关系密切。 结论 脑梗死后智能障碍是多因素相互作用的结果 ,与梗死灶数量、体积、脑萎缩及脑白质疏松等多种因素有关。

Objective To explore the effect factors of intelligence impairment in cerebral infarct patients Methods The intelligence level of 249 cases of cerebral infarct patients identified by CT findings were tested by Hasegawa Dementia Scale To analyze the correlation among the occurrence of intellectual impairment and sex,age,education level,the major risk of stroke(hypertension and diabetes),the quantity and extent of focal lesions and the pressense of cerebral atrophy or subcortical degeneration in 106 cerebral infarct dementia index cases and 143 cerebral infarction without dementia index cases Results 106 (42 6% ) of the cerebral infarction patients were shown to have intelligence impairment,including dementia(24 9%)and pre-dementa(17 7%) The intellectual impairment was relative to age,sex ,education level,the major risk of stroke,cerebral atrophy,subcortical degeneration and the quantity and extent of focal lesion Conclusions It was suggested that a single explanation for cerebral infarct impairment is not adequate,Rather,multiple factors including quantity and extent of focal lesions,pathologic changes of cerebral atrophy,subcortical chronic brain circulation disorder,low education level and so on may independently contribute to cerebral infarct intellectual impairment