期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

人类化学因子受体基因多态性与艾滋病

The correlation between human chemical factor receptor genetic polymorphism and AIDS
原文传递
导出
摘要 不同个体感染HIV 1后其临床过程及预后可有较大差别。决定个体易感性及病程进展的因素是综合性的 ,包括病毒、宿主及环境等因素。 The clinical course and outcome of HIV 1 infection are highly variable among individuals.Factors that influence susceptibility to infection and disease progression include virus,host,and environment.Here we provide a brief review of the reported chemical factor receptor genetic polymorphism associated with progression of AIDS.
作者 卢洪洲 潘孝彰
机构地区 复旦大学附属华山医院传染病科
出处 《临床内科杂志》 CAS 北大核心 2003年第8期393-395,共3页 Journal of Clinical Internal Medicine
关键词 艾滋病 化学因子受体 基因多态性 CCR5 CXCR4 HIV 1 Chemical factor Genetic polymorphism AIDS
分类号 R512.91 [医药卫生—内科学]
  • 相关文献

参考文献9

  • 1Michael D, Marry C, Stephen JO. Balanced polymorphism selected by genetic versus infectious human disease. Annu Rev Genomics Genet,2002,3:263-292.
  • 2Kittchai P, David HM, Carlos MG ,et al. Associations of chemokine system polymorphisms with clinical outcomes and treatment responses of chronic heoaitis C. Gastroenterology ,2003,124:352-360.
  • 3Carzino DA, Devico AL, Conant KE, et al. The role of chemokines in human immunodeficiency virus infection, Immunol Rev.2000,177:79-87.
  • 4Cao X, Nelson GW, Karacki P, et al. Effect of a single amino acid change in MHC class Ⅰ molecules on the rate of progression to AIDS. N Engl J Med,2001,344:1668-1675.
  • 5Wang F,Jin L,Lei Z,et al. Genotypes and polymorphisms of mutant CCRS-delta 32, CCR2-64I and SDF1-3' a HIV-1 resistance alleles in indigenous Han Chinese. Chin Med J ,2001,114 : 1162-1166.
  • 6Kato H ,Tsuchiya N, Izumi S, et al. New variations of human CC-chemokine receptors CCR3 and CCR4. Genes Immun, 1999,1:97-104.
  • 7Evans DT, Piekarczyk MS, Allen TM, et al. Immunodominance of a single CTL epitope in a primate species with limited MHC class Ⅰ polymorphism. J Immunol, 1997,159 : 1374-1382.
  • 8Smith MW, Dean M, Carrington M, et al. Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression.Science, 1997,277 : 959 -965.
  • 9David HM, Cynthia AK, Michael P, et al. Genetic polymorphism in CX3CR1 and risk of HIV disease. Science, 2000,290 : 2031.
临床内科杂志
2003年 第8期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部