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热敏灸治疗过敏性鼻炎有效性的系统评价及Meta分析 被引量:10

Efficacy of heat-sensitive moxibustion in treatment of patients with allergic rhinitis:A Meta-analysis
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摘要 目的系统评价过敏性鼻炎患者行热敏灸治疗与其他常规疗法的效果。方法检索中国期刊全文数据库(CNKI)、中国生物医学文献数据库(SinoMed)、维普中文科技期刊全文数据库和万方数据库以及外文Medline(from 1948),Cochrane Library(for all years),Web of Science(from 1926),纳入所有使用热敏灸治疗过敏性鼻炎的临床随机对照试验(RCT),应用RevMan5.3软件对所提取的数据进行异质性检验,由检验结果选定随机效应模型对数据进行合并分析。结果最终纳入7项RCT,共计568例患者。Meta分析结果显示:热敏灸组的有效率显著高于其他常规治疗组(OR=3.31,95%CI:2.16~5.09,P<0.05),差异有统计学意义;进一步的亚组分析得出热敏灸组的有效率分别高于西药组(OR=3.26,95%CI:1.81~5.88,P<0.05)、针刺组(OR=2.93,95%CI:1.41~6.10,P<0.05)、普通艾灸组(OR=4.85,95%CI:1.43~16.42,P<0.05),差异均有统计学意义。鼻部症状体征的改善率,热敏灸组显著高于其他常规治疗组(OR=-1.54,95%CI:-1.97~-1.12,P<0.05),差异有统计学意义。结论热敏灸治疗过敏性鼻炎比其他疗法效果更好,由于纳入文献数量少、样本量少、质量偏低,存在偏倚风险,今后仍需更多大样本多中心的高质量随机对照试验验证。 Objective To systematically evaluate the effect of heat-sensitive moxibustion and other conventional therapies in patients with allergic rhinitis.Methods CNKI,SinoMed,VIP,WanFang Data,Medline(from 1948),Cochrane Library(for all years)and Web of Science(from 1926)were searched for associated studies to collect clinical randomized controlled trial(RCT)by treatment of allergic rhinitis with heat-sensitive moxibustion.Meta-analysis was performed with Revman 5.3 software.Results A total of 7 studies were including 568 patients.The Meta-analysis showed that:the effective rate in the heat-sensitive moxibustion was significantly higher than that of other conventional treatment groups(OR=3.31,95%CI:2.16~5.09,P<0.05);further subgroup analysis showed that the effective rate of heat-sensitive moxibustion was significantly higher than those of drug group(OR=3.26,95%CI:1.81~5.88,P<0.05),acupuncture group(OR=2.93,95%CI:1.41~6.10,P<0.05)and general moxibustion group(OR=4.85,95%CI:1.43-16.42,P<0.05).For the improvement rate of nasal symptoms and signs:heat-sensitive moxibustion was significantly higher than that of other conventional treatment groups(OR=-1.54,95%CI:-1.97^-1.1 2,P<0.05).Conclusions Heat-sensitive moxibustion in treatment of patients with allergic rhinitis was more effective than other therapies.Due to the small number of included studies,small sample size,and low quality,there is risk of bias.More large-scale,multi-center,high-quality randomized controlled trials are still needed to further confirm the results in the future.
作者 董文华 李小丽 李俊雄 田宁 DONG Wen-hua;LI Xiao-li;LI Jun-xiong;TIAN Ning(Guangdong Province Hospital of Integrated Traditional Chinese and Western Medicine)
出处 《热带医学杂志》 CAS 2019年第4期422-425,共4页 Journal of Tropical Medicine
基金 佛山市科技创新项目(2017AG100252) 国家中医药管理局2017年度"中医药传统知识保护与发展"专项(GZY-KJS-2017-05)
关键词 热敏灸 过敏性鼻炎 META分析 Heat-sensitive moxibustion Allergic rhinitis Meta-analysis
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