三磷酸腺苷与硝普钠控制性降压对血流动力学影响的比较

Comparative Study of Hemodynamic Effects of Induced Hypotension by ATP and Nitroprusside

在30例中青年病人中,分组比较了 ATP 与 SNP 降压对血流动力学的影响。在两组中 MAP和 SVR 降低非常显著(P<0.01)。HR 增快和 CVP 降低在 SNP 组非常显著,而 ATP 组则无明显变化(P>0.05)。停药后10min MAP 和 SVR 在 ATP 组很快回到降压前水平,而 SNP 组则高于降压前和对照组水平(P<0.05)。

The hemodynamic changes of ATP and SNP induced hypotension were studied in 30 patients.Result showed that MAPand SVR decreased significantly in both groups,as compared with control group,HR increased and CVP decreased markedly inSNP group(P<0.01),while ATP group showed no meaningful change(P>0.05).Ten minutes after weaning,MAP andSVR in ATP group quickly returned to prehypotensive level,in SNP group exceeded prehypotensive and control levels.