盆炎净胶囊治疗气滞血瘀型慢性盆腔炎临床研究

Clinical Study on Penyanjing Capsules for Chronic Pelvic Inflammation of Qi Stagnation and Blood Stasis Type

目的:观察盆炎净胶囊治疗气滞血瘀型慢性盆腔炎的临床疗效。方法:将气滞血瘀型慢性盆腔炎患者90例随机分为对照组和观察组,各45例;对照组给予注射用哌拉西林钠静脉滴注;观察组在对照组的基础上加用盆炎净胶囊口服,2组疗程均为7天;观察2组临床疗效及治疗前后C-反应蛋白(CRP)、降钙素原(PCT)、白细胞(WBC)、临床症状积分变化,并记录不良反应发生情况。结果:总有效率观察组为95.55%,对照组为71.11%,2组比较,差异有统计学意义(P <0.05)。治疗后,2组患者CRP、PCT、WBC值均较治疗前降低(P <0.05),且观察组上述指标均低于对照组(P <0.05)。治疗后,2组临床症状总积分均较治疗前下降(P <0.05),且观察组临床症状总积分低于对照组(P <0.05)。2组患者治疗过程中均未出现明显不良反应。结论:盆炎净胶囊治疗气滞血瘀型慢性盆腔炎疗效显著,且安全性较好。

Objective: To observe the clinical effect of Penyanjing capsules for chronic pelvic inflammation of qi stagnation and blood stasis type. Methods: Divided 90 cases of patients with chronic pelvic inflammation of qi stagnation and blood stasis type into the control group and the observation group randomly, 45 cases in each group. The control group received piperacillin by intravenous drip for three to five days continuously. The observation group additionally received Penyanjing capsules orally for two weeks continuously based on the treatment of the control group. Observed the clinical effect and the changes of C-reactive protein(CRP), procalitonin(PCT), white blood cell(WBC) and scores of clinical symptoms before and after treatment in the two groups, and recorded the adverse reactions. Results: The total effective rate was 95.55% in the observation group and was 71.11% in the control group,the difference being significant(P < 0.05). After treatment, values of CRP, PCT and WBC in the two groups were decreased when compared with those before treatment(P < 0.05), and the above indexes in the observation group were obviously lower than those in the control group(P < 0.05). After treatment,scores of clinical symptoms in the two groups were decreased when compared with those before treatment(P < 0.05), and the score in the observation group was obviously lower than that in the control group(P < 0.05). No adverse reaction was found during the treatment in the two groups. Conclusion: The therapy of Penyanjing capsules for chronic pelvic inflammation of qi stagnation and blood stasis type has significant effect and good safety.