耳穴贴压联合加味生化汤防治产后出血临床研究

Clinical Study on Therapy of Auricular Point Sticking Combined with Modified Shenghua Tang in Preventing and Treating Postpartum Hemorrhage

目的:观察耳穴贴压联合加味生化汤防治产后出血的临床效果。方法:选取84例在本院生产的产妇为研究对象,随机分为对照组和观察组各42例。对照组采用催产素联合卡孕栓治疗,观察组在对照组基础上加用耳穴贴压联合加味生化汤。记录2组产后4 h、6 h及12 h出血量,检测产妇治疗前后纤维蛋白原(FIB)、活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)及血小板计数(BPC)水平,观察2组不良反应发生情况。结果:观察组产后2 h、6 h及12 h出血量均少于对照组,差异均有统计学意义(P <0.05)。治疗后,2组BPC、PT、APTT水平均较治疗前降低(P <0.05),FIB水平均较治疗前提高(P <0.05);观察组BPC、PT、APTT水平均低于对照组(P <0.05),FIB水平高于对照组(P <0.05)。2组恶心呕吐、血压升高、潮红、发热发生率比较,差异均无统计学意义(P> 0.05)。结论:耳穴贴压联合加味生化汤,能有效减少产后出血量,改善产妇的凝血功能,安全性较高。

Objective: To observe the therapy of auricular point sticking combined with modified Shenghua tang in preventing and treating postpartum hemorrhage. Methods: 84 parturients in our hospital were selected as study objects, and were randomly divided into the control group and the observation group, with 42 cases in each group. The control group was treated with oxytocin combined with Carboprost Methylate Suppositories. The observation group was treated with auricular point sticking combined with modified Shenghua tang based on the treatment of the control group. The amount of postpartum bleeding at the 4th, 6th,and 12th hour was recorded, the levels of fibrinogen(FIB), activated partial thrombin time(APTT),prothrombin time(PT) and blood platelet count(BPC) were measured before and after treatment, and adverse reactions were observed in the two groups. Results: The amount of postpartum bleeding at the 4th, 6th, and 12th hour in the observation group was less than that in the control group respectively, differences being significant(P < 0.05). Compared with those before treatment,levels of BPC,PT and APTT in both groups decreased after treatment(P < 0.05), and the FIB levels increased after treatment(P < 0.05). The levels of BPC, PT and APTT in the observation group were all lower than those in the control group(P < 0.05), and the FIB level was higher than that in the control group(P < 0.05). The incidence of nausea and vomiting,elevated blood pressure,flushing and fever in the two groups was not statistically significant(P > 0.05). Conclusion: The therapy of auricular point sticking combined with modified Shenghua tang can effectively reduce the amount of postpartum bleeding, improve the coagulation function of parturients with great safety.