肾阴虚模型制备方法及肾阴虚证研究进展

Research Progress of the Preparation Methods of the Model of Kidney Yin Deficiency and Kidney Yin Deficiency Syndrome

目前在中医理论指导下,应用现代药理实验方法建立的中医证候模型,已成为研究中医证候实质、阐释中医药治疗疾病机理的有效途径。肾阴虚证模型已成为公认的中医证候模型。近几十年来,研究者应用现代科学技术,从临床观察到动物实验、从功能到形态、从组织器官到细胞蛋白等对肾阴虚证进行了探索。对肾阴虚证的表征和本质有了较全面的认识,对肾阴虚证模型的建立和评价方法取得了较好的成果。本文综述了近年来肾阴虚模型建立的方法和肾阴虚的现代研究概况。

At present,under the guidance of Chinese medicine theory,the model of Chinese medicine syndrome built by modern pharmacological experimental methods has become the effective way to explore the essence of Chinese medicine syndrome and to explain the mechanism of Chinese medicine treating diseases. The model of kidney yin deficiency syndrome has been recognized as the model of Chinese medicine syndrome. In recent decades,researchers have explored the kidney yin deficiency syndrome by modern science and technology from clinical observation to animal experiment,from function to morphology,from tissue organ to cell protein and so on. The characterization and nature of the kidney yin deficiency syndrome have been relatively comprehensively understood,and the better results in the establishment and evaluation of the model of kidney yin deficiency syndrome have been achieved. This paper reviewed the methods to establish the model of kidney yin deficiency in recent years and the modern research situation of kidney yin deficiency.