基于数据挖掘探讨中风后失语的立方特点

Discussion on Characteristics of Prescriptions for Aphasia After Stroke Based on Data Mining

目的:从文献中探寻中风后失语的立方特点,为现代医者治疗本症提供参考。方法:检索并提取《中华医典5.0》系统中古代及近代医籍中治疗中风后失语的中药方剂,利用Excel 2013软件建立"中风后失语方剂"数据库,应用Spss Modeler18.0软件对数据库进行频数和关联分析,生成可视化的网络分析图以直观显示关联分析结果。结果:治疗中风后失语常用药物有甘草、防风、川芎、附子、生姜、肉桂等。最常见的归经为肝、肺、脾、胃、肾、心。药味比的前3位药类为补虚药、解表药、清热药。药物常由温里、补虚、解表、活血之品组成。结论:中风后失语的立方特点独具特色,主要体现为从肺论治、解表清热与适用凉开3个方面。

Objective:To investigate the characteristics of prescriptions for aphasia after stroke from literature,and to provide references for modern physicians in the treatment of this disease. Methods:Retrieved and extracted the Chinese herbal prescriptions for the treatment of aphasia after stroke in ancient and modern medical books from the Chinese Medical Classic System 5.0. Established a database of Prescriptions for Aphasia After Stroke by using Excel 2013 software. Conducted a frequency and association analysis of the database with Spss Modeler 18.0 software and generated a visual network analysis chart to display the results of the association analysis directly. Results:The commonly used Chinese herbal medicine in the treatment of aphasia after stroke included Radix et Rhizoma Glycyrrhizae,Radix Saposhnikoviae,Rhizoma Chuanxiong,Radix Aconiti Lateralis Praeparata,Rhizoma Zingiberis Recens,Cortex Cinnamomi,etc. The most common meridian entries of the medicine were the liver,lung,spleen,stomach,kidney,and heart. The top three medicinal types in the ratio of medicinal flavors were the deficiency-tonifying,exterior-releasing,and heat-clearing medicine. Most of the medicine could warm the interior,tonify deficiency,release the exterior,and invigorate the blood. Conclusion:The characteristic of prescriptions for aphasia after stroke is unique,which is mainly reflected in three aspects:treating from the lung based on syndrome differentiation,releasing the exterior and clearing heat,as well as applying cold prescriptions for resuscitation.