补肾化瘀法联合黄体酮治疗先兆性流产临床研究

Clinical Study on Method of Supplementing Kidney and Dissolving Stasis Combined with Progesterone for Threatened Abortion

目的:观察补肾化瘀法联合黄体酮治疗先兆性流产的临床效果及对生殖内分泌激素水平的影响。方法:将86例先兆性流产患者按照随机数字表法随机分为2组各43例。对照组给予黄体酮治疗,联合组给予补肾化瘀法联合黄体酮治疗。比较2组临床疗效及治疗前后孕酮(P)、雌二醇(E_2)、β型人绒毛膜促性腺激素(β-HCG)等性激素水平的差异。结果:联合组总有效率为90.70%,对照组为67.44%,2组比较,差异有统计学意义(P <0.05)。治疗前,2组患者性激素水平比较,差异无统计学意义(P> 0.05)。治疗后,2组性激素水平均升高(P <0.05),联合组升高幅度较对照组显著(P <0.05)。结论:先兆性流产患者应用补肾化瘀法联合黄体酮治疗可有效改善性激素水平,取得良好的临床疗效。

Objective:To observe the clinical effect of the method of supplementing kidney and dissolving stasis combined with progesterone for threatened abortion and its effect on the level of reproductive endocrine hormone. Methods:A total of 86 cases of patients with threatened abortion were divided into two groups according to the random number table method,43 cases in each group. The control group was given progesterone for treatment,while the combination group additionally received the method of supplementing kidney and dissolving stasis based on the treatment of the control group. The clinical effect and the changes in the levels of sex hormones before and after treatment such as the progesterone(P),estradiol(E2),and β-human chorionic gonadotropin(β-HCG) in the two groups. Results:The total effective rate was 90.70% in the combination group and 67.44% in the control group,the difference being significant(P < 0.05). Before treatment,there was no significant difference being found in the comparisons of the the levels of the involved sex hormones between the two groups(P > 0.05). After treatment,the levels of the involved sex hormones in the two groups were increased(P < 0.05),while the increase in the combination group was more significant than that in the control group(P < 0.05). Conclusion:The levels of sex hormones can be effectively improved by the method of supplementing kidney and dissolving stasis combined with progesterone for patients with threatened abortion,and with good clinical effect.