祛风宣肺健脾法治疗小儿过敏性咳嗽风邪犯肺证临床研究

Clinical Study on Method of Dispelling Wind, Diffusing the Lung and Fortifying the Spleen for Allergic Cough with Pathogenic Wind Attacking the Lung Syndrome in Children

目的:观察祛风宣肺健脾法治疗小儿过敏性咳嗽急性期风邪犯肺证的临床疗效。方法:将60例患儿随机分为治疗组和对照组各30例,对照组给予氯雷他定糖浆口服,治疗组在对照组基础上给予祛风宣肺健脾中药为主治疗,7天为1疗程,治疗2疗程后统计疗效。结果:对照组治愈10例,显效16例,有效2例,无效2例;治疗组治愈17例,显效11例,有效1例,无效1例,2组临床疗效比较经秩和检验,差异有统计学意义(P <0.05)。治疗后,2组咳嗽程度、咳嗽频率评分均较治疗前降低(P <0.05),且治疗组两项评分明显低于对照组(P <0.05)。治疗后,治疗组IgE水平较治疗前及对照组治疗后明显降低,差异均有统计学意义(P <0.05);对照组IgE水平治疗前后变化不大(P> 0.05)。结论:祛风宣肺健脾法配合氯雷他定糖浆口服治疗小儿过敏性咳嗽急性期疗效显著,效果优于单纯西药治疗。

Objective:To observe the clinical effect of the method of dispelling wind,diffusing the lung and fortifying the spleen for acute stage of allergic cough with pathogenic wind attacking the lung syndrome in children.Methods:A total of 60 cases of children were divided into the treatment group and the control group randomly,30 cases in each group.The control group was given oral administration of loratadine syrup,while the treatment group was additionally treated with Chinese medicine for dispelling wind,diffusing the lung and fortifying the spleen as main treatment based on the treatment of the control group.The treatment lasted for 7 days and the curative effect in the two groups were observed after 2 courses of treatment.Results:In the control group,there were 10 cured cases,16 cases with marked effect,2 effective cases and 2 ineffective cases.In the treatment group,there were 17 cured cases,11 cases with marked effect,1 effective case and 1 ineffective case.Compared the clinical effect in the two groups,the difference being significant(P<0.05).After treatment,scores of the cough degree and the frequency of cough in the two groups were decreased when compared with those before treatment(P<0.05),and the two scores in the treatment group were obviously lower than those in the control group(P<0.05).After treatment,the level of IgE in the treatment group was obviously decreased when respectively compared with that in the treatment group before treatment and that in the control group after treatment,differences being significant(P<0.05);there was little change of the level of IgE in the control group before and after treatment(P>0.05).Conclusion:The therapy of the method of dispelling wind,diffusing the lung and fortifying the spleen combined with oral administration of loratadine syrup has significant curative effect in treating allergic cough in children at acute stage.