宣肺平喘汤治疗小儿咳嗽变异性哮喘风寒袭肺证55例临床研究

Clinical Study on Xuanfei Pingchuan Tang for 55 Cases of Cough Variant Asthma with Wind-cold Attacking the Lung Syndrome in Children

目的:探讨宣肺平喘汤治疗小儿咳嗽变异性哮喘(CVA)风寒袭肺证的疗效。方法:选择110例CVA患儿,按随机数字表法分为观察组和对照组各55例。对照组采取孟鲁司特钠咀嚼片和硫酸特布他林片治疗,观察组在对照组基础上采取宣肺平喘汤治疗;连续治疗1个月。比较2组风寒袭肺证症状评分、咳嗽症状评分。比较2组治疗1个月后的疗效。结果:观察组总有效率为96.36%,明显高于对照组(81.82%)(P <0.05)。治疗后,2组风寒袭肺证症状(咳嗽、咳痰、咽痒)评分较治疗前明显减少(P <0.01)。观察组治疗后风寒袭肺证(咳嗽、咳痰、咽痒)症状评分明显低于对照组(P <0.01)。治疗后,2组夜间、日间咳嗽症状积分较治疗前减少(P <0.01)。治疗后,观察组夜间、日间咳嗽症状积分显著低于对照组(P <0.01)。结论:在常规西药基础上加宣肺平喘汤辨治小儿CVA,可明显改善患儿相关指标和咳嗽症状,提高临床疗效,值得临床借鉴。

Objective:To explore the curative effect of Xuanfei Pingchuan Tang on cough variant asthma(CVA) with wind-cold attacking the lung syndrome in children. Methods:Selected 110 cases of children with CVA and divided them into the observation group and the control group randomly according to the random number table,55 cases in each group. The control group was treated with montelukast sodium chewable tablets and terbutaline sulfate tablets,the observation group was treated with Xuanfei Pingchuan tang based on the treatment of the control group. The two groups received continuous treatment for one month. Compared the symptom scores of wind-cold attacking the lung syndrome and cough in the two groups. Compared the curative effect of the two groups after one month of treatment. Results:The total effective rate was 96.36% in the observation group,which was obviously higher than that of 81.82% in the control group(P < 0.05). After treatment,the symptom scores of wind-cold attacking the lung syndrome(cough,expectoration,throat itching) in both groups were obviously decreased when compared with those before treatment(P < 0.01). After treatment,the symptom score of wind-cold attacking lung syndrome(cough,expectoration,throat itching) in the observation group was obviously lower than that in the control group(P < 0.01). After treatment,the symptom scores of cough at night and daytime in both groups were obviously decreased when compared with those before treatment(P < 0.01). After treatment,the symptom score of cough at night and daytime in the observation group was obviously lower than that in the control group(P < 0.01). Conclusion:Based on the routine western medicine,the therapy of Xuanfei Pingchuan decoction for children with CVA can obviously improve the related indexes and the symptom of cough in children. The improvement of the clinical efficacy is worthy of clinical reference.