肾经标本配穴为主针灸治疗肾虚痰浊证轻度认知功能障碍临床研究

Clinical Study on Acupuncture Therapy with A Focus on Kidney Channel Biao-ben Acupoints for Mild Cognitive Impairment with Kidney-deficiency and Phlegm-turbidity Syndrome

目的:观察肾经标本配穴为主针灸治疗肾虚痰浊证轻度认知功能障碍(MCI)的临床疗效。方法:将MCI患者60例随机分为2组各30例,治疗组予以肾经标本配穴为主针灸治疗,对照组予以尼莫地平口服治疗,疗程均为8周;应用中医证候积分、简易智力状态检查量表(MMSE)、蒙特利尔认知量表(MoCA)进行评估治疗效果。结果:总有效率治疗组为90.00%;对照组为36.67%,2组比较,差异有统计学意义(P <0.05)。治疗后2组中医证候积分、MMSE、MoCA量表评分均较治疗前明显改善(P <0.05),且治疗组上述各项积分改善较对照组更显著(P <0.05)。结论:肾经标本配穴为主针灸治疗MCI肾虚痰浊证疗效显著,值得临床推广应用。

Objective:To observe the clinical effect of the acupuncture therapy with a focus on Kidney Channel Biao-ben Acupoints for mild cognitive impairment(MCI) with kidney-deficiency and phlegm-turbidity syndrome. Methods:A total of 60 cases of patients with MCI were randomly divided into two groups,30 cases in each group. The treatment group mainly received the acupuncture therapy with a focus on point combinations on kidney meridian based on the theory of manifestation and root cause for treatment,and the control group was treated with oral administration of nimodipine. The course of treatment in the two groups lasted for eight weeks. The curative effect was assessed by the adoption of the Chinese medicine syndrome score,Mini-Mental Status Examination(MMSE) and Montreal Cognitive Assessment(MoCA). Results:The total effective rate was 90.00% in the treatment group and 36.67% in the control group,the difference being significant(P < 0.05). After treatment,the scores of Chinese medicine syndrome,MMSE and MoCA were significantly improved when compared with those before treatment(P < 0.05),and the above indexes in the treatment group were improved more significantly than those in the control group(P < 0.05). Conclusion:The acupuncture therapy with a focus Kidney Channel Biao-ben Acupoints has significant therapeutic effect in treating patients with MCI with kidney-deficiency and phlegm-turbidity syndrome,and is worthy of clinical promotion and application.