麻黄升麻汤证病机量化分析

A Quantitative Analysis of the Pathogenesis of Syndromes of Mahuang Shengma Tang

目的:量化分析麻黄升麻汤的配伍特点,进一步分析麻黄升麻汤证的病机。方法:收集《伤寒论》中有明确药物组成的方剂,不同剂量、不同炮制方法的同种药物需分为不同的对象处理。运用双层频权剪叉算法,计算每个药物的功效权值,进而计算麻黄升麻汤的功效权值以及判定强度级别,最终得出麻黄升麻汤证的病机特点。结果:麻黄升麻汤Ⅲ级功效有补心、补肾、清肺、温经、祛风、除痹、化痰、止痛、消痈、止咳、化饮;Ⅱ级功效有消肿、治头痛、润肺、清胃、利咽、补血、解毒、解表;Ⅰ级功效有补肺、敛肺、补脾、益胃、滋阴、敛阴、生津、润燥、补气、清热、散寒、利水、止泻、平喘、除烦、治心悸;-Ⅰ级功效有温肺、温脾、潜阳;-Ⅱ级功效有温胃。麻黄升麻汤的病机在于心肾虚寒而肺脾胃热,气阴亏虚而痰湿困阻,以及阳气内郁。结论:麻黄升麻汤主治心肾虚寒,肺脾胃热,气阴亏虚,痰湿困阻,并能发散郁邪。

Objective:To conduct a quantitative analysis of the combination characteristics of Mahuang Shengma tang so as to further analyze the pathogenesis of syndromes of Mahuang Shengma tang.Methods:The combination prescriptions with specific medicine in Shanghan Lun were collected.The same medicine was analyzed as different subjects according to different dosages and processing methods.The weight value of effect of each medicine was calculated by the adoption of a double-level algorithm for frequency and weight so that the weight value of effect of Mahuang Shengma tang was calculated and its strength level was determined,and the characteristics of the pathogenesis of syndromes of Mahuang Shengma tang were analyzed.Results:Mahuang Shengma tang at stageⅢcan tonify the heart,tonify the kidney,clear lung heat,warm the meridians,dispel wind,eliminate impediment,resolve phlegm,relieve pain,disperse abscesses,suppress cough and dissolve fluid retention;the one at stageⅡcan disperse swelling,treat headaches,moisten the lung,clear stomach heat,soothe the throat,tonify blood,detoxify and release the exterior;the one at stageⅠcan tonify the lung,constrain the lung,tonify the spleen,boost the stomach,enrich yin,constrain yin,engender fluid,moisten dryness,tonify qi,clear heat,dissipate cold,promote urination,arrest diarrhea,calm panting,reduce vexation and treat palpitations;the one at stage-Ⅰcan warm the lung,warm the spleen and subdue yang;the one at stage-Ⅱcan warm the stomach.The pathogenesis of Mahuang Shengma tang lied in the heat of the stomach,lung and spleen caused by heart-kidney deficiency cold and the phlegm-damp retention caused by qi-yin depletion as well as the internal depression of yang-qi.Conclusion:Mahuang Shengma tang is mainly used to treat heart-kidney deficiency cold,heat of the stomach,lung and spleen,qi-yin depletion and internal depression of yang-qi,and it can dispel stagnant pathogen.