郑绍周治疗多发性硬化组方用药规律分析

Analysis on Administration Laws of Prescriptions of Zheng Shaozhou in Treating Multiple Sclerosis

基于数据挖掘技术,分析郑绍周教授治疗多发性硬化(Multiple Sclerosis,MS)的组方用药规律。收集整理郑绍周教授门诊处方,严格筛选后录入中医传承辅助系统,对数据进行频次分析、关联规则分析、熵聚类分析。对282张处方进行分析,发现使用频次≥90次的药物共20味,包括黄芪、重楼、全蝎、葛根等;核心处方由13味药物组成;发现8组新处方。郑绍周教授治疗MS以补肾健脾、解毒通络为主要治则。

Based on data mining technology,the authors analyzed the administration laws of prescriptions of Professor Zheng Shaozhou in treating multiple sclerosis(MS).The outpatient clinic prescriptions of Professor Zheng Shaozhou were collected and rigorously screened and then recorded in the Chinese medicine inheritance platform system.Then the frequency analysis,correlation rule analysis and entropy cluster analysis were carried out.After analyzing 282 prescriptions,the authors found that 20 herbs were used for over 90 times(≥90),including Astragalus(Huangqi),Rhizoma Paridis(Chonglou),Scorpio(Quanxie),Radix Puerariae(Gegen);the core prescription consisted of 13 herbs;8 new prescriptions were found.Professor Zheng Shaozhou mainly treated MS with the rule of tonifying the kidney and strengthening the spleen and dispelling toxins and dredging collaterals.