中药灌肠对危重症感染合并胃肠道功能障碍的临床研究

Effect Study on Herbal Enema for Infection in Critical Illness Complicated with Gastrointestinal Dysfunction

目的:观察中药灌肠对危重症感染合并胃肠道功能障碍患者的临床疗效。方法:选取104例危重症感染合并胃肠道功能障碍患者,按随机数字表法分为观察组和对照组各52例。对照组进行常规治疗,观察组在对照组基础上进行中药灌肠治疗。观察并记录2组患者治疗后的相关指标,包括肛门排气时间、肠鸣音恢复时间、肠内营养时间、开始排便时间,并比较2组治疗前与治疗后肠胃功能的变化情况。观察2组患者治疗后的不良反应发生情况,不良反应包括恶心、呕吐、腹胀和皮疹。结果:观察组临床总有效率为98.08%,对照组总有效率为82.69%,2组比较,差异有统计学意义(P <0.05)。治疗后,观察组开始排便时间、肠鸣音恢复时间、肠内营养时间、肛门排气时间均小于对照组(P <0.05)。治疗前,2组胃肠功能评分比较,差异无统计学意义(P> 0.05)。治疗后,观察组胃肠功能评分低于对照组(P <0.05)。观察组不良反应发生率为3.85%,对照组为21.25%,2组比较,差异有统计学意义(P <0.05)。结论:对危重症感染合并胃肠道功能障碍患者实施中药灌肠治疗,可以降低患者治疗后的不良反应发生率,缩短患者肛门排气和肠鸣音恢复时间,改善患者的胃肠功能,能够有效提高临床治疗效果,具有显著的临床应用价值。

Objective:To observe the effect on herbal enema for infection in critical illness complicated with gastrointestinal dysfunction.Methods:104 cases of patients with infection in critical illness complicated with gastrointestinal dysfunction were selected and divided into the observation group and the control group according to random number table method,52 cases in each group.The control group was given routine treatment,while the observation group was additionally treated with herbal enema based on the treatment of the control group.Relevant indicators including the anal exhaust time,the recovery time of bowel sound,the enteral nutrition time and the beginning time of defecation in the two groups were observed and recorded after treatment,and the changes of gastrointestinal function before and after treatment were compared.The adverse reactions after treatment were observed in both groups,including nausea,vomiting,abdominal distension and rash.Results:The total clinical effective rate of the observation group was 98.08%,and that of the control group was 82.69%,the difference being significant(P<0.05).After treatment,the beginning time of defecation,the recovery time of bowel sound,the enteral nutrition time and the anal exhaust time in the observation group were shorter than those in the control group(P<0.05).Before treatment,there was no significant difference being found in gastrointestinal function score in the two groups(P>0.05).After treatment,the gastrointestinal function score of the observation group was lower than that of the control group(P<0.05).The incidence of adverse reactions was 3.85%in the observation group and21.25%in the control group,the difference being significant(P<0.05).Conclusion:The therapy of herbal enema for infection in critical illness complicated with gastrointestinal dysfunction can reduce the incidence of adverse reactions after treatment,shorten the anal exhaust time and the recovery time of bowel sound,and improve the gastrointestinal function of patients.It can effectively improve the clinical therapeutic effect and has significant clinical value.