活血健腰汤对腰椎间盘突出症患者术后疼痛及腰椎功能的影响

Effect of Huoxue Jianyao Tang on Postoperative Pain and the Lambar Vertebrae Function of Patients with Lumbar Disc Herniation

目的:观察活血健腰汤对腰椎间盘突出症患者术后腰椎功能的影响。方法:选取行腰椎间盘突出症手术患者80例,随机分为对照组和观察组各40例。对照组采用甲钴胺片联合塞来昔布胶囊治疗,观察组在对照组治疗基础上加用活血健腰汤,从术后第1天开始,连续服用2周。治疗后统计优良率,观察2组生活质量、腰椎功能、腰椎疼痛程度的改善情况及不良反应发生情况。结果:观察组优良率90.0%,对照组优良率72.5%,2组比较,差异有统计学意义(P <0.05)。治疗后,2组健康状况调查简表(SF-36)评分、日本骨科协会评估治疗分数(JOA)均较治疗前提高,视觉模拟评分法(VAS)评分均较治疗前降低,差异均有统计学意义(P <0.05);观察组SF-36、JOA评分均高于对照组,VAS评分低于对照组,差异均有统计学意义(P <0.05)。观察组出现1例轻度腹泻,1例恶心,对症处理后缓解。2组均未见肝肾功能指标异常。结论:对腰椎间盘突出症患者术后采用活血健腰汤治疗,能够显著缓解患者术后疼痛,促进腰椎功能恢复,提高生活质量,安全性高。

Objective:To observe the effect of Huoxue Jianyao tang on the postoperative pain and the lumbar vertebrae function of patients with lumbar disc herniation.Methods:A total of 80 cases of patients after surgical treatment of lumbar disc herniation were randomly divided into the control group and the observation group,40 cases in each group.The control group was treated with Mecobalamin tablets combined with Celecoxib capsules,and the observation group was additionally treated with Huoxue Jianyao tang based on the treatment of the control group.The treatment lasted for two weeks since the first day after operation.After treatment,the excellent-and-good rate was counted,and the improvement of the quality of life,the lumbar vertebrae function and the lumbar pain,and adverse reactions in the two groups were observed.Results:The excellent-and-good rate was 90.0%in the observation group and 72.5%in the control group,the difference being significant(P<0.05).After treatment,the scores of Short Form-36 Health Survey(SF-36)and Japanese Orthopaedic Association(JOA)in the two groups were increased when compared with those before treatment,and the scores of Visual Analogue Scale(VAS)in the two groups were decreased when compared with those before treatment,differences being significant(P<0.05);the scores of SF-36 and JOA in the observation group were higher than those in the control group,and the score of VAS in the observation group was lower than that in the control group,differences being significant(P<0.05).In the observation group,there was one case of mild diarrhea and one case of nausea,and both were alleviated after symptomatic treatment.The indexes concerning the liver and the kidney function showed no abnormality in both groups.Conclusion:The application of Huoxue Jianyao tang on patients after the operation of lumbar disc herniation can relieve the postoperative pain,promote the recovery of lumbar vertebrae function,enhance the quality of life and possess high drug safety.