缩宫祛瘀汤联合米非司酮配伍米索前列醇治疗稽留流产临床研究

Clinical Study on Suogong Quyu Tang Combined with the Concerted Application of Mifepristone and Misoprostol for Missed Abortion

目的:探讨缩宫祛瘀汤联合米非司酮配伍米索前列醇治疗稽留流产临床研究。方法:将稽留流产患者86例按照随机数字表法分为2组各43例,对照组给予米非司酮配伍米索前列醇治疗,治疗组在对照组治疗基础上给予缩宫祛瘀汤治疗,观察2组患者的孕囊排出时间,阴道出血时间和失血量,观察临床疗效以及不良反应。结果:2组患者孕囊排出时间、阴道出血时间和失血量比较,差异有统计学意义(P <0.05)。治疗后,完全流产率对照组为62.79%,治疗组为81.40%,2组流产情况比较,差异有统计学意义(P <0.05)。对照组不良反应总发生率为46.51%,治疗组为44.19%,2组比较,差异无统计学意义(P> 0.05)。结论:经验方缩宫祛瘀汤联合米非司酮配伍米索前列醇治疗稽留流产患者,疗效好,减少出血,安全性良好。

Objective:To discuss the clinical effect of Suogong Quyu tang combined with the concerted application of mifepristone and misoprostol for missed abortion.Methods:A total of 86 patients with missed abortion were divided into two groups according to the random number table method,43 cases in each group.The control group was treated with the concerted application of mifepristone and misoprostol,and the treatment group was treated with Suogong Quyu tang based on the treatment of the control group.The time of gestational sac discharge,the time of vaginal bleeding,the blood loss,the clinical effect and the adverse reactions in the two groups were observed.Results:The time of gestational sac discharge,the time of vaginal bleeding and the blood loss in the two groups were compared,the difference being significant(P<0.05).After treatment,the complete abortion rate was 62.79%in the control group and 81.40%in the treatment group,the difference being significant(P<0.05).The total incidence of adverse reactions was 46.51%in the control group and 44.19%in the treatment group,there being no significance in the difference(P>0.05).Conclusion:The therapy of Suogong Quyu tang combined with the concerted application of mifepristone and misoprostol has significant curative effect in treating missed abortion and can reduce bleeding wth good safety.