解毒养阴含漱液联合护理措施干预放射性口腔炎疗效分析

Analysis of Curative Effect of Jiedu Yangyin Gargle Combined with Nursing Measures on Radiation Stomatitis

目的:观察解毒养阴含漱液联合护理措施干预放射性口腔炎的疗效。方法:将98例放射性口腔炎患者随机分为对照组和观察组各49例。对照组给予康复新液含漱,观察组给予解毒养阴含漱液漱口。2组均给予基础口腔护理,饮食、心理、疼痛护理指导。评定2组患者的放射性口腔炎程度、疼痛程度[数字疼痛评分法(NRS)评分]、口腔损害程度[口腔评估指南(OAG)评分)]和健康状况[卡氏功能状态量表(KPS)评分]。结果:治疗后,观察组放射性口腔炎程度、口腔疼痛程度均轻于对照组,差异均有统计学意义(P <0.05)。2组NRS、OAG评分均较治疗前下降(P <0.01),观察组NRS、OAG评分均低于对照组(P <0.01)。对照组KPS评分较治疗前下降(P <0.01),观察组KPS评分与治疗前比较,差异无统计学意义(P> 0.05);观察组KPS评分高于对照组(P <0.01)。结论:采用解毒养阴含漱液治疗放射性口腔炎,并给予相应的口腔护理指导,可有效减轻患者的口腔炎反应程度和疼痛,稳定患者的生活质量,从而有利于保证放射治疗顺利完成。

Objective:To observe the curative effect of Jiedu Yangyin Gargle combined with nursing measures on radiation stomatitis.Methods:A total of 98 cases of patients with radiation stomatitis were randomly divided into the control group and the observation group,49 cases in each group.The control group was given Kangfuxin Gargle for gargling,and the observation group was given Jiedu Yangyin Gargle.The two groups were both given basic oral nursing and the nursing instructions on diet,psychology and pain.The degree of radiation stomatitis,the scores of pain by Numeric Rating Scale(NRS),the scores of oral damage by Oral Assessment Guide(OAG)and the scores of health status by Karnofsky Performance Status(KPS)in the two groups were evaluated.Results:After treatment,the degree of radiation stomatitis and the score of oral pain in the observation group were lower than those in the control group,differences being significant(P<0.05).The scores of NRS and OAG in the two groups were decreased when compared with those before treatment(P<0.01).The scores of NRS and OAG in the observation group were lower than those in the control group(P<0.01).The KPS score in the control group was decreased when compared with that before treatment(P<0.01).There was no significant difference being found in the comparison of the KPS score in the observation group before and after treatment(P>0.05).The KPS score in the observation group was higher than that in the control group(P<0.01).Conclusion:The therapy of Jiedu Yangyin Gargle combined with oral nursing instructions for radiation stomatitis can effectively reduce the responses caused by stomatitis and the pain,stabilize the quality of life of patients,so as to ensure the smooth completion of radiotherapy.