裸花紫珠分散片治疗慢性盆腔炎临床研究

Clinical Study on Luohua Zizu Dispersible Tablets for Chronic Pelvic Inflammation

目的:观察裸花紫珠片治疗慢性盆腔炎临床疗效。方法:将慢性盆腔炎患者87例随机分为2组,对照组43例和观察组44例,对照组给予常规西药抗炎治疗,观察组在此基础上加用裸花紫珠分散片联合治疗。记录2组患者治疗前后血清相关炎症因子白细胞总数(WBC)及血沉(ESR)变化;观察2组患者治疗前后疼痛视觉模拟评分(VAS)的变化;观察治疗后2组患者总有效率以及不良反应发生率。结果:治疗后2组血清WBC、ESR均较治疗前下降(P <0.05),但与对照组比较,观察组指标下降更为明显(P <0.05)。2组治疗后VAS评分均较治疗前下降(P <0.05),与对照组比较,观察组VAS得分下降更为显著,差异有统计学意义(P <0.05)。观察组总有效率90.9%,对照组为79.1%,2组比较,差异有统计学意义(P <0.05)。观察组不良反应发生率4.5%,对照组为2.3%,2组比较,差异无统计学意义(P> 0.05)。结论:在传统西药消炎治疗基础上给予裸花紫珠分散片联合治疗慢性盆腔炎,可更加有效降低炎症反应,更有效保护患者生殖系统功能,减少疼痛,增加治疗有效率,但不增加药物副反应,表明联合治疗比单独传统西药抗炎治疗更加安全有效,提高患者生活质量,改善女性生殖健康。

O bjective:To observe the clinical effect of Luohua Zizu dispersible tablets for chronic pelvic inflammatory disease.Methods:Divided 87 patients with chronic pelvic inflammatory disease randomly into two groups,43 cases in the control group and 44 cases in the observation group.The control group was given routine anti-inflammatory treatment in western medicine,while the observation group was additionally treated with Luohua Zizu dispersible tablets.Recorded the changes of serum-related inflammatory factors such as white blood cell count(WBC)and erythrocyte sedimentation rate(ESR)in the two groups before and after treatment.Observed the changes of visual analogue scale(VAS)of patients in the two groups before and after treatment.Observed the total effective rate and incidence of adverse reactions in the two groups after treatment.Results:After treatment,the serum WBC and ESR of the two groups were lower than those before treatment(P<0.05);compared with that in the control group,the decrease of this index in the observation group was more obvious(P<0.05).The VAS scores of the two groups were lower than those before treatment(P<0.05).Compared with that in the control group,the VAS score in the observation group decreased more significantly,difference being significant(P<0.05).The total effective rate was 90.9%in the observation group and 79.1%in the control group,compared the two groups,difference being significant(P<0.05).The incidence of adverse reactions was 4.5%in the observation group and 2.3%in the control group,compared the two groups,no significant difference being found between the two groups(P>0.05).Conclusion:The application of Luohua Zizu dispersible tablets based on anti-inflammatory treatment in traditional western medicine for chronic pelvic inflammatory disease can effectively reduce the inflammatory response,protect the reproductive system function of patients,reduce pain and increase the effective rate of the treatment without increasing the side effects of drugs.It shows that the combined treatment is safer and more effective than anti-inflammatory treatment in traditional western medicine and can improve quality of life in patients and promote female reproductive health.