从中医气血津液论述自噬治疗恶性肿瘤的理论依据

A Discussion on Theoretical Basis of Autophagy for Malignant Tumors from the Theory of Qi,Blood,Fluid and Humor in Chinese Medicine

自噬作为细胞存活的机制,在肿瘤的发生发展及治疗上发挥着双重作用。肿瘤的发生是气血津液失调的结果,自噬的功能与中医气血津液密切相关。笔者通过从气、血、津液三方面辨析自噬治疗恶性肿瘤的病机特征,提出从气虚、气滞、瘀血、痰瘀毒结等论治,从而为自噬治疗肿瘤提供中医理论依据。

Autophagy,as a mechanism of cell survival,plays a dual role in the development and treatment of tumors.The occurrence of tumors is the result of the disharmony of qi,blood,fluid and humor.The function of autophagy is closely related to qi,blood,fluid and humor in Chinese medicine.The authors discriminated the characteristics of pathogenesis of autophagy for malignant tumors from three aspects including qi,blood as well as fluid and humor,and put forward that the treatments should focus on qi deficiency,qi stagnation,blood stasis and phlegm-stasis-toxin bind,so as to provide theoretical basis of Chinese medicine for the treatment of tumors by autophagy.