整合针灸方案治疗轻中度抑郁症临床研究

Clinical Study on Integrated Acupuncture and Moxibustion Regimen in Treating Mild-to-moderate Depression

目的:观察整合针灸方案治疗轻中度抑郁症的临床疗效及对患者生存质量的影响。方法:将101例轻中度抑郁症患者随机分为综合组、针艾组、针刺组,综合组采用整合针灸方案治疗,针艾组采用针刺配合艾柱灸,针刺组只针刺治疗,每天1次,每周治疗2次,3组疗程均为12周。分别于治疗前后、治疗后1个月进行汉密尔顿抑郁量表(HAMD)、SF-36生存质量量表评分,评价临床效果。结果:治疗后、治疗后1个月,3组HAMD评分均较治疗前下降,差异有统计学意义(P <0.05)。治疗后,综合组和针艾组HAMD评分低于针刺组(P <0.05)。治疗后1个月,综合组HAMD评分低于针艾组、针刺组(P <0.05)。治疗后,综合组总有效率为88.24%,针艾组为82.35%,针刺组为51.52%,综合组和针艾组显著高于针刺组(P <0.05)。治疗后1个月,综合组总有效率为79.41%,针艾组为47.06%,针刺组为42.42%,综合组显著高于针艾组和针刺组(P <0.05)。治疗后、治疗后1个月,3组患者SF-36各维度评分均较治疗前升高(P <0.05)。治疗后、治疗后1个月,综合组SF-36各维度评分均高于针艾组、针刺组(P <0.05)。结论:整合针灸方案治疗轻中度抑郁症近远期疗效显著,能提高患者的生存质量,值得临床推广。

Objective:To observe the clinical effect of the integrated acupuncture and moxibustion regimen in treating mild-to-moderate depression and its effect on the quality of life of patients.Methods:A total of 101 patients with mild-to-moderate depression were randomly divided into the comprehensive group,the acupuncture and moxibustion group and the acupuncture group.The comprehensive group was treated with integrated acupuncture and moxibustion regimen;the acupuncture and moxibustion group was treated with acupuncture and moxibustion with moxa cone,and the acupuncture group was solely treated with needling.All groups were treated once a day and twice a week.The course of treatment in the three groups was twelve weeks.Before and after treatment and one month after treatment,the scores of Hamilton Depression Scale(HAMD)and Short Form 36-item Health Survey(SF-36)were evaluated and the clinical effect was observed.Results:After treatment and one month after treatment,scores of HAMD in the three groups were decreased when compared with those before treatment,the difference being significant(P<0.05).After treatment,the HAMD scores in the comprehensive group and the acupuncture and moxibustion group were lower than those in the acupuncture group(P<0.05).One month after treatment,the HAMD score in the comprehensive group was lower than those in the acupuncture and moxibustion group and the acupuncture group(P<0.05).After treatment,the total effective rate was 88.24%in the comprehensive group,82.35%in the acupuncture and moxibustion group,and 51.52%in the acupuncture group.The ones in comprehensive group and acupuncture group were significantly higher than that in the acupuncture group(P<0.05).One month after treatment,the total effective rate was 79.41%in the comprehensive group,47.06%in the acupuncture and moxibustion group,and 42.42%in the acupuncture group.The one in the comprehensive group was significantly higher than those in the acupuncture group and acupuncture and moxibustion group(P<0.05).After treatment and one month after treatment,SF-36 scores of all dimensions in the three groups were increased when compared with those before treatment(P<0.05).After treatment and one month after treatment,SF-36 scores of all dimensions in the comprehensive group were higher than those in the acupuncture and moxibustion group and the acupuncture group(P<0.05).Conclusion:The integrated acupuncture and moxibustion scheme has significant short-term and long-term effect in treating mild-to-moderate depression,and can improve the quality of life of patients,which is worthy of clinical promotion.